levodopa stimulation GH test

The levodopa GH test is performed by the principle that levodopa is a precursor of dopamine, which is converted to dopamine or norepinephrine in the body, excitatory hypothalamic-pituitary, and stimulates growth hormone releasing hormone (GHRH)-GH. Release. This test is suitable for understanding the reserve function of suspected pituitary dwarf patients. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Tips: Pay attention to the normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Normal value [Normal value] After taking levodopa, serum GH increased by more than 3 ug/L. Clinical significance Abnormal results: serum GH in patients with pituitary GH deficiency is less than 3ug/L. Adult growth hormone deficiency often has fewer or no symptoms. But in children, it can cause growth retardation and even become a dwarf. People who need to be examined: Suspected pituitary pygmy patients need to understand the pituitary GH reserve function. Precautions 1. About half of the patients who took levodopa had nausea, vomiting water, dizziness, dry mouth and soft body. They were generally not serious and disappeared after half an hour. 2. In this trial, only 70% of males responded, 90% of children responded, and almost 100% of normal women responded. Therefore, patients who did not respond to levodopa should be tested for other GH stimuli. Forbidden before examination: pay attention to normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Requirements for inspection: Actively cooperate with the doctor's request. Oral levodopa was given on an empty stomach in the morning, and the amount of adult and child was different. Inspection process [method] 1, early morning fasting levodopa 0.5g (adult), children 10mg / Kg body weight (body weight 15Kg oral 0.125g, 15-30Kg oral 0.25g, greater than 30Kg oral 0.5g). 2, 2 ml of blood was collected at 0, 60, 90, 120 min, and the serum was separated by -20 oc. Not suitable for the crowd Inappropriate crowd: temporarily unknown. Adverse reactions and risks No obvious complications and harms.