growth hormone challenge test

The growth hormone challenge test is to stimulate the secretion of growth hormone with arginine hydrochloride to determine whether the growth hormone reserve function is normal. Features: Pulsed secretion, age-related, the most secretory pulse in the middle of puberty, the most secreted. Peak: The secretion reaches a peak one hour after bedtime, and the secretion is more than half of the total amount of the day. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Tips: Pay attention to the normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Normal value The increase in growth hormone in normal people is at least 7 μg / L or 3 times higher than the basal value, and the peak value is 60 to 120 minutes. Clinical significance When the growth hormone reserve is insufficient, the peak value is <7μg/L, which is often used for the diagnosis of short stature and dwarfism. Abnormal results: Insufficient growth hormone reserve due to lesions. People who need to be examined: short stature and dwarfism patients. Low results may be diseases: pediatric craniopharyngioma, pituitary dwarf disease, idiopathic puberty delay, pediatric growth hormone deficiency, dwarfism precautions Forbidden before examination: pay attention to normal diet, pay attention to normal work and rest, and prevent endocrine disorders. After 8 pm, fasting overnight, the next morning in bed. Blood was taken to check the basic growth hormone. Requirements for inspection: Actively cooperate with the doctor's request. If the solution leaks under the skin during injection, it may cause redness and pain in the local tissue and should be avoided. Inspection process method: After 8:00 pm, fasting overnight, the next morning in bed. Blood was taken to check the basic growth hormone. 2 arginine hydrochloride 0.5g / kg body weight, diluted with water for injection to a total amount of 200ml, dripped in 30 minutes. After 30 drops, 60, 90 and 120 minutes after the drop of the drug, blood was taken from the other upper limb to measure growth hormone. Not suitable for the crowd Inappropriate people: arginine should be used with caution in severe liver or kidney disease or diabetes with acidosis. Adverse reactions and risks No obvious complications and harms.