metoclopramide (MCP) stimulation PRL test

Metoclopramide (MCP) Excitatory PRL test is carried out by the following principle: the hypothalamus secretes an inhibitory factor (PIF) to inhibit the secretion of PRL, PIF is dopamine, MCP is a dopamine receptor antagonist, which can fight dopamine against PRL. Inhibition, while promoting the secretion of PRL. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: fasting Tips: Pay attention to the normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Normal value The peak of normal people is >3 times higher than the baseline value (generally 5-10 times), and women's response is higher than that of men. The peak occurs at 15-30 minutes (the peak of oral therapy occurs in 30-60 minutes). Clinical significance Abnormal results: simple or functional lactation is a normal reaction. Partial pituitary dysfunction and pituitary prolactinoma are weak and weak, with a peak increase of less than 3 times. The peak dysfunction of the anterior pituitary gland is less than 2 times. The people who need to be examined are: patients with suspected partial pituitary dysfunction, pituitary prolactinoma, anterior pituitary dysfunction and other related diseases. Low results may be diseases: precautions for amenorrhea and galactorrhea syndrome Forbidden before examination: pay attention to normal diet, pay attention to normal work and rest, and prevent endocrine disorders. Requirements for inspection: Actively cooperate with the doctor's request. Inspection process method: 1, MCP10mg, intravenous injection in one minute (oral dose does not change). 2. PRL was determined by collecting 2,0 ml of serum from the forearm at 0, 15, 30, and 45 minutes (the blood was collected at 0, 30, 60, 90, and 120 points by oral method). Result analysis: If the subject's PRL peak is 576, 7ug/L, and the peak value is increased by <2 times, appearing at 60 minutes, the pituitary prolactinoma diagnosis is supported. Not suitable for the crowd Inappropriate crowd: temporarily unknown. Adverse reactions and risks No obvious complications and harms.