calcium challenge test

The calcium challenge test is because the calcium ion in the gastric cavity can promote the secretion of gastrin from the G cells of the antrum. Therefore, after intravenous infusion of a certain amount of calcium, the serum gastrin value is continuously monitored to help the high. Differential diagnosis of gastrinoma, gastric antrum G cell hyperplasia and duodenal ulcer in gastric acidosis. Basic Information Specialist classification: Digestive examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Not suitable for people: hypercalcemia or suffering from hyperparathyroidism. Normal value The test was positive. Clinical significance Abnormal results: 1. Pro-gastrin test positive. 2. Gastric sinus G cell hyperplasia or hyperfunction test can be positive. 3. The duodenal ulcer test is negative, and the serum gastrin can be slightly increased, that is, 400 pg/ml. Need to check the crowd: patients with gastrinoma. Precautions Taboo before inspection: none Taboo during examination: When intravenous infusion of calcium gluconate, strictly control the concentration of the drug and the rate of instillation, and do not drip too fast, so as to avoid cardiac arrest and other complications, and prepare medicines and instruments for rescue. Inspection process On the morning of the test day, the rats were fasted, venous blood was collected, and gastrin was used as a basic control. Intravenous infusion of calcium gluconate 5 mg / kg body weight · h for 3 h. After the calcium injection, the venous blood was taken once every 30 minutes, and the serum was induced by gastrin for 8 times. Not suitable for the crowd Not suitable for people: hypercalcemia, or suffering from hyperparathyroidism. Adverse reactions and risks There are no related complications and hazards.