Direct bilirubin

Direct bilirubin is also known as bilirubin. Unconjugated bilirubin is transformed in hepatocytes, combined with glucuronic acid to form conjugated bilirubin, and bilirubin is directly reacted with Vanden's qualitative test, so this bilirubin is called direct bilirubin. . Determination of direct bilirubin is mainly used to identify the type of jaundice. Combined with the increase of bilirubin, it indicates that the excretion of bilirubin from the biliary tract after hepatocyte treatment and treatment is impaired. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: No clinical significance. Normal value: Direct bilirubin: 0-6.84μmol/L Above normal: Elevation is seen in hepatic jaundice, obstructive jaundice, neonatal hyperbilirubinemia, rotor syndrome, chronic active hepatitis, cirrhosis, sepsis, falciparum malaria, extensive burns, and hypothyroidism. negative: Positive: Tips: Please cooperate with the doctor when checking. Normal value 0 to 6.84 μmol/L. Clinical significance Elevation is seen in hepatic jaundice, obstructive jaundice, neonatal hyperbilirubinemia, rotor syndrome, chronic active hepatitis, cirrhosis, sepsis, falciparum malaria, extensive burns, and hypothyroidism. High results may be diseases: pediatric jaundice hepatic pigmentation syndrome, congenital choledochal cyst in children, congenital biliary atresia in neonates, congenital choledochal cyst, pregnancy with cirrhosis, acute yellow, gallstone, cirrhosis of the elderly, newborn Herpes simplex virus infection precautions (1) Sample requirements: Serum samples should be used to avoid sample illumination and hemolysis, and hemolysis may interfere with the determination. (2) Physiological fluctuations: 40% variation during the day. Specimen storage is directly reduced by light exposure. (3) Drug effects: drugs that cause liver damage or hemolysis. Inspection process 2 ml of fasting venous blood was taken and placed in a dry tube for examination to avoid hemolysis of the specimen. Detection operation: After fully mixing the reagent, the wavelength is 600nm, the control tube is zeroed, and the absorbance of each tube is read; or the zero is adjusted with distilled water, the absorbance of the measuring tube and the control tube is read, and the difference between the absorbance of the measuring tube and the absorbance of the control tube is used (AU) -AC), the corresponding bilirubin concentration was found on the standard curve. Not suitable for the crowd Generally no taboos. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.