Anti-egg zona pellucida antibody (AZP)

Anti-egg zona pellucida antibody: This is an autoimmune infertility antibody that occurs in women, an anti-transparent band (a transparent band is a glycoprotein that coats the surface of an egg). The cause of this is that during the menstrual cycle, there will always be follicles in which follicles become locked. If the activity is transparent, it may become an antigenic stimulus, resulting in anti-Zona pellucida antibodies, or the transfection of the zona pellucida due to infection, resulting in irritation. The body produces anti-clear zone antibodies. Basic Information Specialist classification: gynecological examination classification: immune examination Applicable gender: whether women are fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Infertility. Tips: Do not take anti-inflammatory drugs before the examination. Normal value The normal result is negative. Clinical significance Abnormal results: anti-Zona pellucida antibody positive clinically found that it is the cause of most of the unexplained infertility female infertility. The researchers confirmed that many infertile women have zona pellucida antibodies in their serum. The zona pellucida can be used as a foreign body to stimulate the body to generate an immune response. When the body is stimulated by a transparent antigen with cross-antigenic antigen, or various pathogenic factors cause translocation of the zona pellucida antigen, it leads to the recognition of the helper T cells in the body, and finally the body produces damage-resistant anti-spatial immunity, which reduces fertility. . People who need to be examined: women who are infertile for a long time after marriage, especially infertile women over the age of 35. Positive results may be diseases: menstrual disorders, infertility, serum anti-sperm antibody-positive infertility, immune infertility precautions Contraindications before the examination: fasting before the examination, can not take anti-inflammatory drugs. Requirements for inspection: Actively cooperate with doctors to do routine inspections. Inspection process Application of mixed lymphocyte culture reaction (MLR) and lymphocyte toxicity antibody assay, determination of anti-sperm antibody, blood group and anti-blood group antibody test for suspected autoimmune disease to detect APA. Not suitable for the crowd Inappropriate people: patients who take antiviral drugs for a long time. Adverse reactions and risks There are no related complications and hazards.