Bone alkaline phosphatase

The concentration of bone alkaline phosphatase in serum is considered to reflect the metabolic activity of osteoblasts, and the accurate evaluation of bone metabolism is important for determining the severity of bone metabolic diseases and therapeutic response. Therefore, in the treatment of osteoarthritis, osteomalacia, primary hyperparathyroidism, renal osteodystrophy, osteoporosis and bone metastases, the detection of serum bone alkaline phosphatase levels has a place. The determination of bone alkaline phosphatase is applied to the diagnosis of osteoarthritis and the detection of the condition. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Pay attention to the serum is not contaminated and promptly sent for inspection. Normal value Female: 1-12 years old is less than 500U/L; more than 15 years old, 40-150U/L; Male: 1-12 years old is less than 500U/L; 12-15 years old, less than 750U/L; more than 15 years old, 40-150U/L. Clinical significance Abnormal results: 1. Physiological increase: Children's alkaline phosphatase activity can be 1 to 2 times higher than that of normal people during physiological bone development. Adolescents in the growing season, as well as pregnant women and foods with high fat content, can rise. 2. Pathological elevation: (1) Skeletal diseases such as rickets, rickets, bone malignant tumors, malignant tumor bone metastasis, etc.; prevention of vitamin D deficiency in children and monitoring of rickets treatment. (2) Hepatobiliary diseases such as extrahepatic biliary obstruction, liver cancer, cirrhosis, capillary cholangitis, etc.; (3) Other diseases such as hyperparathyroidism. 3. Pathological reduction is seen in severe chronic nephritis, thyroid insufficiency in children, anemia, etc. People who need to be examined: Children generally require an examination, and those with related diseases and symptoms can also be examined. High results may be diseases: vitamin D deficiency, rickets, osteochondrosis considerations Forbidden before examination: Quantitative detection of serum bone alkaline phosphatase (BAP) requires fasting blood test, preferably in the morning. Requirements for inspection: pay attention to serum is not contaminated and promptly sent for inspection. Inspection process Biochemical markers are a useful indicator in the monitoring of bone metabolic diseases. Urinary hydroxyproline levels and serum total alkaline phosphatase levels have been used to monitor the therapeutic effects of osteoarthritis. Osteoporosis, a relatively minor process of bone remodeling relative to osteoarthritis, requires more sensitive and specific markers. To this end, OCTEIAOstase® provides the laboratory with a method for the quantitative determination of serum bone alkaline phosphatase (BAP), which has now been shown to be effective in the diagnosis and treatment of bone metabolic diseases. Not suitable for the crowd Inappropriate people: no special requirements. Adverse reactions and risks There are no related complications and hazards.