Interleukin 1 (IL-1)

Interleukin 1 is a cytokine produced by monocytes, endothelial cells, fibroblasts, and other types of cells in response to infection. There are two types of IL-1α and IL-1β, both of which bind to the same receptor of the immunoglobulin superfamily. It stimulates the production of cytokines such as colony stimulating factor and platelet growth factor and produces interleukin-2 in T cells, which plays a role in immune response and tissue repair. Interleukin-1 is present in the form of IL-1α and IL-1β. Basic Information Specialist classification: growth and development check classification: immunological examination Applicable gender: whether men and women apply fasting: fasting Tips: Avoid testing after strenuous exercise. Normal value The level of IL-1β in the synovial fluid of patients with synovial fluid containing IL-1β was (90.51±5.03) pg/ml. Clinical significance Abnormal results: (1) Local low concentration - immune regulation synergistically stimulates APC and T cell activation, promotes B cell proliferation and secretion of antibodies. (2) Large-scale production - endocrine effect induces acute phase protein synthesis in the liver; causes fever and cachexia. People to be examined: patients with rheumatoid arthritis, and patients with immunodeficiency. Low results may be diseases: rheumatoid arthritis in the elderly, high incidence of rheumatoid arthritis scleritis in humans may be diseases: kidney damage in rheumatoid arthritis, kidney damage in rheumatoid arthritis Contraindications before the test: Do not take anti-inflammatory drugs (or stop the drug two days before the test). Requirements for inspection: Always maintain the purity of the serum sample and avoid contact with allergens. Inspection process The serum IL-1β content was determined by ELISA. Not suitable for the crowd Inappropriate crowd: None. Adverse reactions and risks There are no related complications and hazards.