indocyanine green test

The indocyanine green (IGG) test is a quantitative test of liver function that mainly reflects liver blood flow and is a sensitive indicator for the diagnosis of compensated liver cirrhosis. More than 90% of ICG can be bound by albumin in the blood after intravenous injection. Therefore, IGG can be injected first and then blood is taken to measure its concentration. Patients who are sensitive to indocyanine green are not suitable for this test. Basic Information Specialist classification: growth and development check classification: liver function test Applicable gender: whether men and women apply fasting: not fasting Tips: It is not suitable for people who are sensitive to indocyanine green. Normal value The retention of 15 min is <10%. Clinical significance Abnormal results ICG reflects the anion transport function of hepatocytes, and is sensitive to the diagnosis of jaundice-free hepatitis or follow-up of its outcome, diagnosis of occult or inactive cirrhosis. Need to check patients with impaired liver function. Low results may be diseases: hepatitis, liver cancer considerations Taboo when checking: 1. Before the examination, the patient is weighed and given a dose of indocyanine green according to its weight. 2. When checking the concentration, adjust the spectrophotometer. 3. After the injection of phthalocyanine green, it takes 15 minutes to completely extract the blood in the body. Inspection process Indigo cyanine green (dose at 0.5 mg/kg body weight) was quickly injected from one arm vein of the patient, and immediately after the injection, 2 ml of blood was drawn from the contralateral arm vein 15 minutes later, and serum was separated. The colorimetric cyanide green concentration value was determined by a spectrophotometer. Calculate the retention rate of indole cyanide green for 15 min, and calculate the formula: the retention ratio of indole cyanide green = (C15 mg% ÷ 1 mg%) × 100%. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. 3. Patients who are sensitive to indocyanine green are not suitable for this test. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.