glucagon stress test

The glucagon load test for the diagnosis of liver disease has been carried out in foreign countries in recent years. It can be used as an ideal indicator for estimating liver storage function. It has important value for the prognosis of liver cirrhosis and liver cancer. The study confirmed that the severity of liver disease patients and liver The storage function is closely related. The blood draw should be fasted. Basic Information Specialist classification: growth and development check classification: liver function test Applicable gender: whether men and women apply fasting: fasting Tips: Patients with advanced liver disease who have liver damage are not eligible for this examination in patients with advanced liver disease who have severe liver function impairment. Normal value The normal human plasma c-AMP (pmol/ml) base value was 24.8, and the c-GMP (pmol/ml) base value was 4.3. Clinical significance Abnormal results plasma c-AMP (pmol / ml) basal value is less than 24.8, c-GMP (pmol / ml) basal value is less than 4.3, for liver cancer, cirrhosis. Need to check the population of liver cancer, cirrhosis patients. Low results may be diseases: liver cirrhosis, liver cancer considerations Taboo before inspection: 1. Be careful not to take the drug before the test, because some drugs will increase the burden on the liver, causing temporary damage to the liver function, which will lead to the accuracy of the liver function test results. 2. Pay attention to ensure adequate sleep before exercise, do not exercise vigorously, which may cause elevated transaminase, thus affecting the test results. 3. You must not drink alcohol the day before. Drinking alcohol will cause an increase in transaminase and affect the test results. 4. Prepare the glucagon physiological saline solution before the examination, pay attention to adjust the PH. Contraindications during examination: The venous blood taken should be fresh and checked immediately. Inspection process After taking blood in the morning, the glucagon was diluted with physiological saline, and the blood was drawn intravenously at 15, 30, and 60 minutes after intravenous injection for 5 minutes. The RIAl method was used to measure c-AMP and c-GMP, and blood was drawn. Other liver function indicators were measured and compared with the results after glucagon load. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.