Four items of liver fibrosis

Four tests of liver fibrosis, namely liver fibrosis, include PCIII (type III procollagen), IV-C (type IV collagen), LN (laminin), and HA (hyaluronidase). This test is mainly used to check the development of the condition and treatment effect of patients with chronic liver disease, and to measure the degree of inflammation activity and the degree of fibrosis. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat before the test, blood test requires fasting, fasting time is generally 8 to 12 hours. Normal value 1. PCIII (type III procollagen) normal range <18 ng / mL. 2. IV-C (type IV collagen) normal range 30-140 ng / mL. 3. LN (laminin) normal range of 50-180 ng / mL. 4. HA (hyaluronanase) normal range <120ng/mL. Clinical significance Abnormal result 1. Slow live liver with continuous pciii, suggesting that the condition may worsen and develop into cirrhosis. 2. The increase of IV-C (type IV collagen) can reflect the degree of liver fibrosis. With the slow migration of liver → slow live liver → liver cirrhosis → liver cancer disease course, IV-C collagen gradually increased in serum. 3. The higher the LN level, the more significant the esophageal varices in patients with cirrhosis. 4. Blood HA is higher than 100 μg / L, indicating the presence of cirrhosis and liver fibrosis. Need to check patients with liver fibrosis, cirrhosis patients. High results may be diseases: liver cirrhosis, liver fibrosis considerations Taboo before inspection: 1. Be careful not to take the drug before the test, because some drugs will increase the burden on the liver, causing temporary damage to the liver function, which will lead to the accuracy of the liver function test results. 2. Pay attention to ensure adequate sleep before exercise, do not exercise vigorously, which may cause elevated transaminase, thus affecting the test results. 3. You must not drink alcohol the day before. Drinking alcohol will cause an increase in transaminase and affect the test results. 4. Accept the patient's consent when undergoing a liver biopsy. Taboo when checking: 1. Can not eat before the examination, blood test requires fasting, fasting time is generally 8 to 12 hours. 2. Take care when performing a liver biopsy, do not hurt the patient. Inspection process Under local anesthesia, a small amount of live liver tissue was taken through a body surface puncture and subjected to pathological examination under a microscope. Not suitable for the crowd It is not appropriate for those who cannot tolerate anesthesia and those who are physically debilitated to avoid serious reactions. Adverse reactions and risks Risk of infection: If you use an unclean device to take a pathological tissue, there is a risk of infection.