Tests reflecting liver cell damage

Tests that reflect hepatocyte damage include serum enzymes and serum iron, which are commonly used in serum enzyme assays such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ACP), and gamma-glutamyl transpeptidase. Enzyme (γ-GT) and so on. Clinically, in various enzyme tests, ALT and AST can sensitively indicate the damage of liver cells and the degree of damage. The acute hepatocyte injury is most sensitive to ALT, and the degree of damage is more sensitive to AST. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: not fasting Tips: Be careful not to take the medicine before the examination. Pay attention to ensure adequate sleep before the examination. You must not drink alcohol the day before. Normal value The normal value of ALT (alanine aminotransferase) is 5-40 U/L for males and 5-35 U/L for females. The normal value of AST (aspartate aminotransferase) is 8-40 U/L. AST/ALT (Valley/Valley) normal value 1.0-2.0. Clinical significance Abnormal results When acute liver damage occurs in early hepatitis, most ALT and cytoplasmic parts of AST are released. Generally, ALT is higher than AST, causing AST/ALT to drop to about 0.56, but if AST is greatly increased, even ALT occurs. The phenomenon of upside down indicates an increase in liver damage. The ratio of AST/ALT in splenic hepatitis and cirrhosis is often >2, and it can also increase in cholestasis and liver cancer. Need to check patients with impaired liver function. High results may be diseases: hepatitis, cirrhosis, precautions Taboo before inspection: 1. Be careful not to take the drug before the test, because some drugs will increase the burden on the liver, causing temporary damage to the liver function, which will lead to the accuracy of the liver function test results. 2. Pay attention to ensure adequate sleep before exercise, do not exercise vigorously, which may cause elevated transaminase, thus affecting the test results. 3. You must not drink alcohol the day before. Drinking alcohol will cause an increase in transaminase and affect the test results. 4. It is best not to eat too greasy, too spicy food the night before. Taboo when checking: 1. Can not eat before the examination, blood test requires fasting, fasting time is generally 8 to 12 hours. 2. Check the morning of the day as far as possible not to exercise or strenuous exercise, if the exercise should go to the hospital after a quiet rest for 20 minutes before taking blood test. Inspection process 6 ml of venous blood was drawn and mounted in a common tube, and the concentrations of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ACP), and γ-glutamyltranspeptidase (γ-GT) were examined. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.