p-Amino hippuric acid synthesis test

The concentration of ammonia hippuric acid in the ammonia hippuric acid synthesis test can be used to estimate the degree of liver damage and its prognosis in patients with liver disease. The heavier the liver is damaged, the worse the ability to metabolize ammonia and the higher the concentration. Eat digestible food for breakfast on the test day. Oral sodium benzoate 3g was orally administered 2 hours after breakfast. The venous blood was taken 1 h after taking the drug to determine the serum p-aminobenzoic acid and the content of aminopurine. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: not fasting Tips: Take care to rest the day before the test, do not drink alcohol, do strenuous exercise. Eat digestible food for breakfast on the test day. Normal value The concentration of ammonia hippuric acid in normal human serum is 40-70 μg/dl. Clinical significance Abnormal results in the serum of the concentration of aminopurine acid is greater than or less than 40 ~ 70μg / dl, may be cirrhosis, hepatitis patients. Need to check the population of liver cirrhosis, hepatitis patients. Precautions Taboo before the test: pay attention to rest the day before the test, do not drink alcohol, do strenuous exercise. Taboo when checking: 1. Eat digestible food for breakfast on the test day. 2. Oral administration of sodium benzoate 3g 2 hours after breakfast. 3. Take venous blood 1 hour after taking the drug. Inspection process 1. Eat digestible food for breakfast on the test day. 2. Oral administration of sodium benzoate 3g 2 hours after breakfast. 3. The venous blood was taken 1 h after taking the drug to determine the serum aminobenzoic acid and the aminopurine content. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.