Arterial blood ketone body ratio determination

The arterial blood ketone body ratio (AKBR) measurement refers to the ratio of acetoacetate to β-hydroxybutyrate in arterial blood. AKBR can accurately reflect liver reserve function. AKBR is also widely used for the evaluation of the efficacy of various liver protection measures. Be careful not to take the drug before the test, because some drugs will increase the burden on the liver, causing temporary damage to the liver function, which will lead to the accuracy of the liver function test results. Pay attention to ensure adequate sleep before exercise, do not exercise vigorously, which may cause elevated transaminase, which will affect the test results. You must not drink alcohol the day before. Drinking alcohol will cause an increase in transaminase and affect the results of the test. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: not fasting Tips: Be careful not to take medication before checking. You must not drink alcohol the day before the test. Normal value The normal value AKBR ≥ 0.7. Clinical significance Abnormal results AKBR <0.7, mitochondrial function is not normal, may not have sufficient oxygen energy supply, leading to liver failure, cirrhosis, liver cancer. Need to check patients with impaired liver function. High results may be diseases: liver cirrhosis, liver cancer precautions Taboo before inspection: 1. Be careful not to take the drug before the test, because some drugs will increase the burden on the liver, causing temporary damage to the liver function, which will lead to the accuracy of the liver function test results. 2. Pay attention to ensure adequate sleep before exercise, do not exercise vigorously, which may cause elevated transaminase, thus affecting the test results. 3. You must not drink alcohol the day before. Drinking alcohol will cause an increase in transaminase and affect the test results. Contraindications during examination: Remember to control the blood glucose concentration during the examination. Inspection process The patient maintained blood glucose at (6.7-11.2) mmol/L 2 ml of brachial artery blood at 10% glucose infusion, and calculated AKBR value = AcAc (acetoacetic acid) / β-OHB (β-hydroxybutyric acid). Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.