progesterone

Progesterone is secreted by the corpus luteum of the ovary and is mainly progesterone (progesterone). After being inactivated into progesterone in the liver, it is excreted in the urine by binding to glucuronic acid. Progestogens often work on the basis of estrogenic effects. Progesterone and estrogen have both antagonistic and synergistic effects. During pregnancy, the two hormones rise in parallel in the blood, peak at the end of pregnancy, and strong contraction of the uterus during childbirth, which is related to the synergistic effect of progesterone and estrogen. Basic Information Specialist classification: maternity check check classification: blood test Applicable gender: whether women are fasting: fasting Tips: When you take blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Normal value <3.1ng/ml during non-pregnancy; 7-10 days of pregnancy>5.0mU/ml; 30 days pregnant>100mU/ml; 40 days of pregnancy>2000mU/ml; 50 to 100 U/ml for 10 weeks of pregnancy; 10 to 20 U/ml for 14 weeks of pregnancy. Clinical significance Abnormal result The test results are low and may have polycystic ovary syndrome. And can prompt for a further gynecological examination. Need to check the crowd: menstrual thin hair, less menstruation, secondary amenorrhea accounted for about 60%, no ovulation menstruation, menorrhagia, excessive frequency or functional uterine bleeding. Low results may be diseases: pregnancy pruritic urticaria papules and plaque disease, miscarriage, spontaneous abortion results may be high disease: endometrial hyperplasia precautions Inappropriate people: People with a significant tendency to bleed. Taboo before the test: Do not eat too greasy, high-protein foods the day before the test, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Sexual intercourse, bathing, vaginal lavage and medication should be prohibited 24 hours before the specimen was taken. Requirements for examination: When taking blood, you should relax your mind to avoid the contraction of blood vessels caused by fear and increase the difficulty of blood collection. Inspection process 1. Sexual intercourse, bathing, vaginal lavage and medication should be prohibited 24 hours before the specimen collection. 2. Check cancer cells: expose the cervix with a vaginal device, gently blot the surface secretions, then use a scraper to rotate clockwise or counterclockwise on the surface of the cervix for 1 week, or use a cervical brush to enter the neck tube. Lcm is rotated for another week, and the scraped secretion is applied to the slide in the same direction. If the fallopian tube cancer or endometrial cancer is suspected, the secretion can be sucked in the neck tube and the posterior iliac crest at the same time. On the film, spread it in one direction. 3. Check the estrogen level: use the vaginal device to open the vagina, use a scraper to 1/3 of the vaginal wall from the mouth, take a small amount of secretions, smear in the same direction on the slide. Unmarried people can use a fine cotton swab dipped in normal saline, squeezed and inserted into the upper part of the vagina, and rotate the material on the side wall. Apply the film in the opposite direction to the slide. 4. All the coated slides should be marked with the number, immediately put into the fixed solution, the slide surface should not touch each other, at least for 15-20min. 5. Fill in and check the cytology checklist, patient name and number on the slide. 6. Smear staining is commonly used for Pap staining, which can be used to check estrogen levels as well as cancer cells. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.