Indirect bilirubin

Indirect bilirubin is also known as unconjugated bilirubin, a bilirubin that does not bind to glucuronic acid. Total bilirubin is composed of indirect bilirubin and direct bilirubin. Increased serum indirect bilirubin is mainly associated with various hemolysis diseases. The reason is that after a large number of red blood cells are destroyed, a large amount of hemoglobin is converted into indirect bilirubin, which exceeds the processing capacity of the liver, and cannot be converted into direct bilirubin, thereby increasing the indirect bilirubin in the blood. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: fasting Tips: Check the need for an empty stomach in the morning. The day before the inspection, it is recommended to ban alcohol. The main component of alcohol, ethanol, is mainly metabolized by the liver and has direct damage to the liver. It can affect the normal operation of liver function to a certain extent, and the accuracy of liver function test results is extremely unfavorable. Normal value 1.0-20.0 μmol/L. Clinical significance Abnormal result 1. Indirect bilirubin is elevated, which is hemolytic jaundice and hepatic jaundice. Increased indirect bilirubin is common in hemolytic diseases, neonatal jaundice or blood transfusion errors. Indirect bilirubin can be elevated in patients with hepatitis and cirrhosis. 2, elevated can also be seen in severe burns, sepsis, malaria, blood group incompatibility, hypersplenism, pernicious anemia, globin-forming anemia, lead poisoning, neonatal physiological jaundice, drug-induced jaundice, constitutional jaundice, breastfeeding Sexual jaundice, etc. High results may be diseases: hemolytic anemia in children, anemia caused by excessive hemolysis, hemolytic anemia induced by pediatric drugs, idiopathic hemosiderosis, pediatric autoimmune hemolytic anemia, congenital erythropoietic abnormal anemia , acute yellow, gallstone, hemolytic anemia, pregnancy with viral hepatitis 1, direct bilirubin increased: seen in primary biliary cirrhosis, biliary obstruction, hepatitis, cirrhosis and so on. 2, indirect bilirubin increased: seen in hemolytic disease, neonatal jaundice or blood transfusion errors. 3, total bilirubin increased: seen in toxic or viral hepatitis, hemolytic jaundice, pernicious anemia, paroxysmal hemoglobinuria. Polycythemia, neonatal jaundice, internal bleeding, hemolytic jaundice after transfusion, acute yellow liver atrophy. Abnormal congenital bilirubin metabolism, fructose intolerance, etc. 4, before checking bilirubin should pay attention to ensure adequate sleep, reasonable diet, do not eat greasy, spicy and other irritating food. Inspection process The subject's blood is drawn and tested by rate or dry chemistry. Not suitable for the crowd Not suitable for people: people who need to be tested have newborns, patients after transfusion, and people with anemia. Those without indications should not be tested. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.