Plasma plasmin-antiplasmin complex assay

The plasma plasmin-antiplasmin complex is a measure of the plasma plasmin-antiplasmin complex in the human body for the diagnosis of fibrinolytic activity and diagnosis of thrombotic diseases. Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. Normal value The ELISA method was 0.8 ug/L. Clinical significance Abnormal result The content is increased. Since the half-life of plasmin, which plays a central role in the fibrinolytic system, is only 0.1 second, it is inconvenient to measure. The indicator used to reflect the fibrinolytic state is to determine the inhibitor of its precursor plasmin or plasmin ( Α2-anti-fibrinolytic inhibitor), by reducing the level of both, it is concluded that the fibrinolytic activity is enhanced, and in recent years, the plasmin-α2 anti-plasmin complex content is measured, and the plasmin is rapidly formed with α2. - Anti-plasmin 1:1 molar formation of complexes to inactivate plasmin, the appearance of PIC directly reflects the formation of plasmin, increased in prethrombotic state and DIC. The elderly population in the population to be examined, with limb pain, swelling, superficial venous engorgement and cords that can be touched along the vein. High results may be diseases: Diffuse intravascular coagulation considerations Taboo before the test: Do not eat too greasy, high-protein foods the day before the test, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Requirements for examination: When taking blood, you should relax your mind to avoid the contraction of blood vessels caused by fear and increase the difficulty of blood collection. Inspection process In the ELISA method, the purified anti-t-PA monoclonal antibody is coated on the enzyme-labeled reaction plate, and the test plasma is added. The t-PA in the plasma is bound to the antibody coated on the reaction plate, and then the enzyme-labeled antibody is added. The enzyme-labeled antibody binds to t-PA bound to the reaction plate, and finally the substrate is added. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.