Plasma protein S determination

The plasma protein S assay is a plasma total protein S (TPS) in plasma including free PS (FPS) and PS (C4bp-PS) bound to complement C4. The measurement is performed to help determine blood diseases. Plasma protein S assay: The test plasma is supplemented with PS matrix plasma (providing other clotting factors other than PS). PS can promote the inhibition of factor Va by APC, the time required for fibrin formation and the plasma to be tested. The amount of FPS is positively correlated. The coagulation time of the subject can be calculated from the standard curve. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. Normal value Plasma total protein S was determined to be 97.56% ± 9.76%. Plasma free protein S (FPS) was determined to be 100.9% ± 29.1%. Clinical significance Abnormal result 1. The plasma total protein S assay is reduced. 2. Plasma free protein S (FPS) assay decreased. Common in congenital and acquired PS deficiency, the latter found in liver disease, oral anticoagulant drugs. The people who need to be examined have weak, weak, sleepy, pale skin, mucous membranes, palpitations, dizziness, headache, tinnitus, vertigo, inattention, and lethargy. Low results may be diseases: fulminant liver failure, liver damage considerations Inappropriate people: newborns, pregnant women. Taboo before the test: pay attention to rest and keep an empty stomach. Requirements for examination: The plasma should be measured as soon as possible, otherwise the plasma should be separated and stored in the refrigerator. Inspection process The PS plasma is added to the test plasma (providing other coagulation factors other than PS), and PS can promote the inhibition of factor Va by APC. The time required for fibrin formation is positively correlated with the amount of FPS in the plasma. The coagulation time of the subject can be calculated from the standard curve. Not suitable for the crowd 1. Patients taking drugs such as oxidative drugs and steroid hormones may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. 3. Pregnant women and newborns are not suitable for this examination. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.