Plasma D-dimer assay

The plasma D-dimer assay is a method for determining the plasma D-dimer in human plasma, and a suspension of the latex particles of the labeled D-dimer monoclonal antibody is added to the plasma to be tested, according to the dilution of the plasma to be tested. The plasma D-dimer content was calculated. A commonly used method for plasma D-dimer assay is latex agglutination: a suspension of latex particles labeled with D-dimer monoclonal antibody is added to the plasma to be tested. If the D-dimer content in plasma is greater than 0.5 mg/L, It binds to the antibody on the latex particles and the latex particles agglomerate. The content of plasma D-dimer can be calculated from the dilution of the plasma to be tested. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: Generally it is normal. Positive: Suggested hypercoagulable or thrombotic disease, or diffuse intravascular coagulation. Tips: When you draw blood, you should relax your mind and avoid the contraction of blood vessels caused by fear. Normal value The plasma D-dimer content was less than 0.5 mg/L and was negative. Clinical significance Abnormal result In DIC, positive or increased is an important basis for the diagnosis of DIC. In the hypercoagulable state and thrombotic disease, the plasma D-dimer content is also increased. D-dimer secondary fibrinolysis is positive or increased, while primary fibrinolysis is negative or not elevated, which is an important indicator for the identification of the two. People who need to be examined have people with symptoms of blood clotting and thrombosis. Positive results may be diseases: thrombosis, diffuse intravascular coagulation considerations Taboo before the test: Do not eat too greasy, high-protein foods the day before the test, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. The results of the examination are susceptible to various drugs and should be stopped before the test. Requirements for examination: When taking blood, you should relax your mind to avoid the contraction of blood vessels caused by fear and increase the difficulty of blood collection. Inspection process Latex agglutination method: a suspension of latex particles labeled with D-dimer monoclonal antibody is added to the plasma to be tested. If the D-dimer content in the plasma is greater than 0.5 mg/L, it binds to the antibody on the latex particles, and the latex particles Then agglutination occurs. The content of plasma D-dimer can be calculated from the dilution of the plasma to be tested. Not suitable for the crowd 1. Patients taking drugs such as oxidative drugs and steroid hormones may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.