Alanine aminotransferase (ALT)

The alanine aminotransferase is mainly present in the hepatocyte cytoplasm, and the intracellular concentration is 1000-3000 times higher than that in the serum. As long as 1% of the liver cells are destroyed, the serum enzyme can be doubled. Therefore, alanine aminotransferase is recommended by the World Health Organization as the most sensitive indicator of liver damage. Formerly known as alanine aminotransferase (GPT). ALT is contained in tissues and organs such as liver, kidney, heart and muscle. Basic Information Specialist classification: Digestive examination classification: liver function test Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: No clinical significance. Normal value: Colorimetric method: 0-35U/L Continuous monitoring method: 6-24U/L Above normal: Increased in liver disease. negative: Positive: Tips: Local congestion, after 24 hours with a warm towel wet, can promote absorption. Normal value Colorimetric method 0 ~ 35U / L; Continuous monitoring method 6 ~ 24U / L. Clinical significance 1. Increased in liver diseases (infectious hepatitis, liver cancer, active cirrhosis, toxic hepatitis, toxic hepatitis, fatty liver, obstructive jaundice), biliary tract disease (cholangitis, cholecystitis), cardiovascular disease (myocardial) Infarction. Hepatic congestion in heart failure), endocrine disease, pancreatic disease, severe diabetes, hyperthyroidism, infectious mononucleosis, malaria, influenza, trauma, severe burns, shock, drug poisoning, and early pregnancy And strenuous exercise. 2, some drugs and poisons, such as chlorpromazine, isoniazid, quinine, salicylic acid preparations, ethanol, lead, mercury, carbon tetrachloride or organic phosphorus, etc., can also cause alanine aminotransferase activity increased . High results may be diseases: liver cirrhosis, ischemic hepatitis, hepatitis B precautions First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, fasting should be done to avoid affecting the test. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. Inspection process Fresh serum or heparin plasma should be measured as soon as possible after collection. It must be stored away from light, avoid using hemolyzed samples, calibrate the calibration, and test after passing the calibration. Not suitable for the crowd Generally for special taboos. Adverse reactions and risks There are generally no special complications or hazards.