Continuous Plasma Protamine Dilution Test

The continuous plasma protamine dilution test is a dilution of protamine added to the plasma to determine whether there is a successful dissolution of the thrombus. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: In normal women, the early stage of menstruation and menstruation may be weakly positive due to the dissolution of fibrin which is locally deposited on the endometrium. The test was positive in 85% of cases of deep venous thrombosis. Tips: Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. Normal value Negative in DIC. Clinical significance Abnormal result Positive for DIC and negative for primary fibrinolysis. In normal women, the early stage of menstruation and menstruation may be weakly positive due to the dissolution of fibrin which is locally deposited on the endometrium. The test was positive in 85% of cases of deep venous thrombosis. In the case of antithrombotic therapy, a positive reaction can be considered as a successful indication of thrombolysis. People who need to be checked In the middle-aged and elderly population, there are limb pain, swelling, superficial venous engorgement and a cord that can be touched along the vein. Positive results may be diseases: venous thrombosis, senile venous thrombosis, primary fibrinolysis Taboo before the test: Do not eat too greasy, high-protein foods the day before the test, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. The patient is in an empty stomach and in a balanced state. Emotional and strenuous exercise nerve tension can cause an increase in PCT. Patients with a coagulation test should discontinue the drug that affects the anticoagulation test for at least one week. Requirements for examination: Do not tie the tourniquet too tightly. The time is not more than half a minute. When collecting venous blood, it is strictly forbidden to beat the blood collection site. It is necessary to “see the blood with one needle” to prevent tissue damage, otherwise it is easy to hemolyze and coagulate; the blood specimen of the indwelling catheter is not suitable. Do a blood coagulation experiment. Inspection process Vascular blood collection was used for testing. Before venous blood collection, carefully check that the needle is securely installed and that there is air and moisture in the syringe. The needle used should be sharp, smooth, ventilated, and the syringe should not leak. Firstly, the skin was disinfected from the inside to the outside and clockwise from the selected venipuncture with a 30g/L iodine swab. After the iodine was volatilized, the iodized trace was wiped out in the same way with a 75% ethanol swab. Fix the lower end of the venipuncture site with the thumb of the left hand, hold the syringe syringe with the thumb and middle finger of the right hand, and fix the needle lower seat with the index finger, so that the bevel of the needle and the scale of the syringe are upward, and the needle is inclined along the vein to make the needle and the skin obliquely penetrate the skin at an angle of 30°. Then, through the vein wall, enter the venous cavity forward at an angle of 5°. After seeing the blood return, the needle will be probed into the spot to avoid the needle slipping out when the blood is collected, but it is not possible to use a deep puncture to avoid hematoma, and immediately remove the cuff. Needle plug can only be pumped out, can not be pushed in, so as to avoid injecting air into the vein to form a gas plug, causing serious consequences. Remove the syringe needle and slowly inject the blood into the anticoagulation tube along the tube wall to prevent hemolysis and foam. Not suitable for the crowd 1. Patients who have taken thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.