Soluble transferrin receptor assay

The soluble transferrin receptor assay is a routine receptor test for soluble transferrin in the human body. The soluble transferrin receptor (sTfR) is derived from the proteolysis of cell surface receptors. In serum, sTfR and different transferrin are present in the form of complexes. About 80% of the sTfR in serum is derived from early red blood cells. When erythropoiesis activity is increased, especially iron deficiency, sTfR synthesis is increased, thus making serum The increase in the concentration of sTfR in the peripheral blood is mainly in the ear lobe blood and fingertips to take blood, the baby can take blood in the heel. The earlobe has a lighter blood pressure, but the blood volume is less, especially those with smaller earlobes are more difficult to take blood. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Normal value 0.9-2.3 mg/L. Clinical significance Abnormal result Increased in hemolytic anemia and iron deficiency anemia, aplastic anemia. Reduced, pure red blood cell aplastic dysfunction, severe aplastic anemia is significantly lower than chronic aplastic anemia. TfR expression in chronic hepatitis, cirrhosis, liver cancer, and psoriasis is also reduced. An increase in the concentration of sTfR has been observed early in the absence of iron. sTfR is a specific test for functional iron status and is not affected by various interfering factors, such as acute or chronic inflammatory reactions, pregnancy, etc. People who need to be checked There are people who are weak and weak, sleepy, pale skin, mucous membranes, palpitations, dizziness, headache, tinnitus, vertigo, inattention, and lethargy. Low results may be diseases: liver cirrhosis, high results of psoriasis may be diseases: iron deficiency anemia, hemolytic anemia, congenital pure red blood cell aplastic anemia, warm antibody type autoimmune hemolytic anemia considerations Taboo before the test: Do not eat too greasy, high-protein foods the day before the test, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Requirements for examination: When taking blood, you should relax your mind to avoid the contraction of blood vessels caused by fear and increase the difficulty of blood collection. Inspection process The peripheral blood mainly has ear lobe blood and fingertips to take blood. The baby can take blood from the heel. The earlobe has a lighter blood pressure, but the blood volume is less, especially those with smaller earlobes are more difficult to take blood. The blood pressure of the fingertips is more obvious, but the blood collection is more, especially for the blood routine test, the stable measurement results can be obtained. The skin should be cleaned before blood collection. Do not take blood immediately after entering the room in the cold outdoor winter. After the body is warm, especially the ear drops and hands should be warmed up. Do not use hot water to heat your hands before taking blood. Keep your fingers dry. If your fingertips have wounds, paronychia, redness or skin disease, avoid using this finger. Fingertip blood collection generally uses the ring finger, because the ring finger will not affect the daily function of the hand after piercing, of course, the middle finger or index finger can also be used, no special difference. When collecting blood in the ear, remove the earrings and other hanging ornaments on the earlobe. Do not hang up immediately after blood collection. After blood collection, apply sterile cotton blocks or other disinfecting hemostatic articles to pinch the needle and puncture the area. Do not touch the dirt. Do not wash your hands immediately. Not suitable for the crowd People with a significant tendency to bleed. Adverse reactions and risks Bleeding: After blood collection, use sterile cotton lump or other disinfecting hemostatic articles to tighten the needle to stop bleeding, especially for patients with coagulopathy should be given sufficient time to avoid bleeding.