β-Lipoprotein Quantification

Β-lipoprotein quantification is a quantitative analysis of β-lipoprotein in vivo. The method uses factor analysis, using the maximum likelihood estimation algorithm, and through the skew rotation, the actual meaning of each factor can be clearly confirmed. Results: The content of various apolipoproteins, triglycerides and cholesterols determined was closely related to the four factors. According to their composition, we further realized that they are VLDL, IDL, LDL. , HDL, and the calculation method for the predicted values ​​of four lipoproteins. Conclusion: Factor analysis can be used to study the composition of lipoprotein and its quantitative prediction, which provides a new way to solve the current difficulties in quantitative analysis of lipoprotein metabolism. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Low β-lipoproteinemia is caused by a mutation in the gene of apoB. Normal value: Male: 1.16-1.42mmol/L Female: 1.29-1.55mmol/L Above normal: May have familial abnormal beta lipoproteinemia. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. Normal value Male: 1.16-1.42 mmol/L. Female: 1.29-1.55mmol/L. Clinical significance Abnormal results: 1. Low β-lipoprotein: Low β-lipoproteinemia is caused by a mutation in apoB gene, and often has no clinical manifestations. 2, no β-lipoprotein: in the complete lack of β-lipoprotein, fat sputum, spinous erythrocytosis (a sharp protrusion on the erythrocyte membrane), retinal pigmentation, movement disorders and intelligent disorders, may be spiked red blood cells Disease; Bassen-Kornzweig syndrome. 3, high β-lipoprotein: may have familial abnormal beta lipoproteinemia (FD), also known as type III hyperlipoproteinemia. It is characterized by a yellow tumor of the skin at the multiple tendons and a yellow tumor of the palm line. People who need to check: People with high blood lipids. High results may be diseases: high-lipoproteinemia type II precautions Pre-inspection contraindications: The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Requirements for examination: When taking blood, you should relax your mind to avoid the contraction of blood vessels caused by fear and increase the difficulty of blood collection. Inspection process Vascular blood collection was used for testing. Before venous blood collection, carefully check that the needle is securely installed and that there is air and moisture in the syringe. The needle used should be sharp, smooth, ventilated, and the syringe should not leak. Firstly, the skin was disinfected from the inside to the outside and clockwise from the selected venipuncture with a 30g/L iodine swab. After the iodine was volatilized, the iodized trace was wiped out in the same way with a 75% ethanol swab. Fix the lower end of the venipuncture site with the thumb of the left hand, hold the syringe syringe with the thumb and middle finger of the right hand, and fix the needle lower seat with the index finger, so that the bevel of the needle and the scale of the syringe are upward, and the needle is inclined along the vein to make the needle and the skin obliquely penetrate the skin at an angle of 30°. Then, through the vein wall, enter the venous cavity forward at an angle of 5°. After seeing the blood return, the needle will be probed into the spot to avoid the needle slipping out when the blood is collected; but it is not possible to use a deep puncture to avoid hematoma, and immediately remove the cuff. Needle plug can only be pumped out, can not be pushed in, so as to avoid injecting air into the vein to form a gas plug, causing serious consequences. Remove the syringe needle and slowly inject the blood into the anticoagulation tube along the tube wall to prevent hemolysis and foam. Not suitable for the crowd People with a significant tendency to bleed. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.