Euglobulin dissolution time

The function of the fibrinolytic system in the body plays a positive role in maintaining the normal flow of blood. The euglobulin lysis time is a preliminary screening test for detecting the function of the fibrinolytic system, which can roughly reflect the fibrinolytic activity. The euglobulin lysis time reflects the function of the fibrinolytic system, shortening (less than 70 min), and the fibrinolytic system function and DIC caused by various causes. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Seen from various causes of fibrinolytic system hyperfunction, DIC. Normal value: Thrombin method: 100-150min Above normal: High is generally normal. negative: Positive: Reminder: Observe the end point without seeing the floc. Normal value Calcium addition method: more than 120min; plus thrombin method: 100-150min. Clinical significance The euglobulin lysis time reflects the function of the fibrinolytic system, shortening (less than 70 min), and the fibrinolytic system function and DIC caused by various causes. Low results may be diseases: diffuse intravascular coagulation, primary fibrinolysis 1. Steps 1 to 2 should be completed within 15 minutes. 2. The observation end point is based on no flocculation. 3. When plasminogen is almost depleted, this test may be a negative reaction. 4. Use borate buffer (pH 9.0) in the calcium addition method instead of barbiturate sodium acetate buffer (pH 7.4). Inspection process 1. Preparation of fibrin plate: 0.3 ml of thrombin and 30 ml of 1.5 g/L fibrinogen were quickly mixed in a glass dish, placed in a horizontal position, and allowed to solidify to form a 1 mm thick fibrin plate. 2. 0.03 ml of the test plasma which was anticoagulated with sodium citrate was dropped on a circle marked on the fibrin plate and placed at 37 ° C for 18 h. 3. Measure the area of ​​the fibrin plate that is dissolved. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.

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