Platelet count (PLT)

Platelet count refers to the number of platelets contained in a unit volume of blood. Platelets are the smallest cells in the blood and protect the integrity of the capillaries. Effective platelet mass and quantity play an important role in collective normal hemostasis. Platelet hemostasis has both mechanically blocked wounds and biochemical adhesion polymerization. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: There are many drugs that can cause elevated or decreased platelets, such as adrenaline, glucocorticoids, etc.; phenytoin, glutamine, phenylbutazone, chlorpromazine, chloramphenicol, cyclophosphamide , vincristine, digitoxin, etc. can reduce thrombocytopenia. Therefore, the above drugs are forbidden before the examination. Normal value (100 ~ 280) × 109 / L. Male: (108 ~ 273) × 109 / L. Female: (148 ~ 257) × 109 / L. Average value: 19 × 109 / L. Clinical significance (1) Physiological variation The number of platelets in healthy people is relatively stable, with no major changes between the day. There is also no significant difference in gender and age. In some women, platelets can be slightly delayed in the periodic (menstrual period). (2) Pathological significance: Thrombocytopenia is seen in primary thrombocytopenic purpura. Some medical conditions such as collagen disease, hypersplenism, uremia, and tumor bone marrow metastasis can cause thrombocytopenia in bone marrow fibrosis. Some hematopoietic disorders such as leukemia, aplastic anemia, hemolytic anemia, myelodysplastic syndrome, etc. may be associated with thrombocytopenia. Platelet depletion in the body, such as disseminated intravascular coagulation and thrombotic thrombocytopenic purpura, sepsis, miliary tuberculosis and other platelets are also often reduced. Significant increases in platelets are mainly seen in essential thrombocythemia, polycythemia vera, chronic myeloid leukemia, and tumor bone marrow metastasis (when there is osteolytic changes). After splenectomy, platelets can also show a transient increase. In addition, platelet reactivity is slightly increased after fractures, bleeding, and surgery. Low results may be diseases: pregnancy with idiopathic thrombocytopenic purpura results may be high disease: relative polycythemia considerations (1) The platelet count can differ by 6% to 10% at different times within one day, which is lower in the morning and slightly higher in the afternoon; lower in spring and slightly higher in winter. (2) The residents in the plain area are lower, the plateau area is higher; the exercise is higher, rest after rest; lower before menstruation, and rise after menstruation. (3) Venous blood is higher than finger blood. (4) Because there are many factors affecting the platelet count, it is difficult to obtain accurate results in one test, and it should be counted several times to determine whether there is any change. (5) There are many drugs that can cause elevated or decreased platelets, such as adrenaline, glucocorticoids, etc.; phenytoin, glutamine, phenylbutazone, chlorpromazine, chloramphenicol, cyclophosphamide , vincristine, digoxigenin, sulfonamides, spironolactone, codeine, tazobactam, diuretic acid, chlorpheniramine, streptomycin, doxycycline, etc. can reduce thrombocytopenia. Inspection process Subjects were venously collected and assayed in time for serum separation. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.