serum free cholesterol

Free cholesterol in serum accounts for about 30% of total cholesterol, which is different under pathological conditions. In clinical tests, only serum total cholesterol is generally measured. If it is necessary to separately measure cholesterol ester and free cholesterol, the free cholesterol fraction in the extract can be determined by using digitonin, and can also be determined by silicic acid chromatography or enzymatic method. . Basic Information Specialist classification: cardiovascular examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Prompt liver lesions. Normal value: Adult: 2.9-6.0mmol/L Children: 3.1-5.2mmol/L Above normal: High cholesterol suggests high blood pressure, high blood fat, coronary heart disease and other hazards. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value Adult: 2.9 ~ 6.0mmol / L. Children: 3.1 to 5.2 mmol/L. Clinical significance The liver is an important organ for cholesterol synthesis. When the function of liver parenchyma cells decreases, the activity of lecithin cholesterol acyltransferase decreases, which affects the esterification of cholesterol. Therefore, patients with severe cirrhosis and hepatitis may not have low serum total cholesterol levels, but esterification. The proportion of cholesterol can be reduced to less than 50% (about 70% in normal). However, this indicator is not sensitive enough and is not suitable as an indicator of liver function. Low results may be diseases: liver cirrhosis, hepatitis precautions If the free cholesterol value of the whole batch is found to be high (both > 30% of total cholesterol), it should be considered whether there is interference with the hydrolysis of cholesterol ester in the reagent. Inspection process Subjects were venously collected and assayed in time for serum separation. It is then determined by enzymatic method. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness.