Serum specific viscosity

Viscosity is an important mechanical property of blood and one of the main contents of blood rheology research. The higher the viscosity, the smaller the rheology, and the greater the opposite. There are many methods for measuring blood viscosity, and serum specific viscosity is often measured in clinic. Reduce hemorrhagic stroke, hematemesis and black feces (upper gastrointestinal bleeding), uterine bleeding, hemorrhagic shock. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Hemorrhagic stroke, hematemesis and black feces (upper gastrointestinal bleeding), uterine bleeding, hemorrhagic shock. Normal value: Male: 1.62-1.70Pa·s Female: 1.63-1.71Pa·s Above normal: Ischemic stroke, myocardial infarction, coronary atherosclerotic heart disease (coronary heart disease). negative: Positive: Tips: Take blood in the morning, try to reduce the amount of exercise before taking blood, do not eat food, keep fasting, you can drink a small amount of water. Normal value Blood viscosity meter method: Male: 1.62 to 1.70 mPa·s. Female: 1.63 to 1.71 mPa·s. Clinical significance (1) increased ischemic stroke, myocardial infarction, coronary atherosclerotic heart disease (coronary heart disease), pulmonary heart disease, thromboangiitis obliterans, arteriosclerotic embolism, tumor, multiple myeloma, original Macroglobulinemia, fibrinogen hyperplasia, polycythemia vera. (2) reduce hemorrhagic stroke, hematemesis and black feces (upper gastrointestinal bleeding), uterine bleeding, hemorrhagic shock. Low results may be diseases: hemorrhagic shock results are high. Possible diseases: hemorrhagic stroke precautions (1) Blood collection and anticoagulation: Improper blood collection can cause viscosity measurement errors. According to the recommendations of ICSH, the compression time of the cuff should be as short as possible. After the needle is inserted, the blood should be collected after the pressure pulse is released for 5 s. When the blood is drawn, the force should not be too strong. The anticoagulant should use a solid anticoagulant to prevent dilution of the blood. If liquid anticoagulation is used, the concentration of the anticoagulant should be increased to reduce the amount of liquid added, usually with heparin or dipotassium edetate or Disodium (EDTA-K: or EDTA-Na2) is anticoagulated, but potassium salt is preferred because of its high solubility. (2) Storage time of sample: It should be tested immediately after blood collection. If stored at room temperature for too long, the measurement result will be too high. It is best to complete the test within 4 hours. If stored in a refrigerator at 4 ° C can be extended to 12 h, blood specimens should not be stored below 0 ° C, because red blood cells will rupture under freezing conditions. (3) Influence of life rhythm: Some studies have pointed out that the blood viscosity of the human body changes regularly in one day, with two peaks at 11 am and 8 pm. Eating can cause changes in hematocrit and plasma composition, so blood collection time is appropriate for early morning fasting. (4) Reference value problem: blood viscosity is the macroscopic performance of internal factors such as plasma viscosity, hematocrit, aggregation and deformation of red blood cells, platelets and white blood cells under certain measurement conditions, and these factors fluctuate within a certain range, so Blood viscosity also has a certain range of fluctuations. Complex changes in blood rheology occur under pathological conditions. Therefore, it is necessary to have a reference value to evaluate whether the blood viscosity is normal. The reference value must be obtained by a person who has undergone strict examination and is in good health. However, the detection rate of diseases in the population depends on the age of the person, the medical knowledge and the level of detection technology, so the reference values ​​are relative. In addition, the living standards and habits of people in different regions have different effects on blood viscosity, so there is no universally applicable reference value, even with common instruments and standardized operation methods. Therefore, different regions and laboratories should have their own reference values. Inspection process (1) Turn on the instrument to warm up and let the constant temperature system reach the test temperature. (2) After the sample is kept at the test temperature for 5 minutes, mix well and add to the sample cup. (3) Press the measurement button and the shear rate is measured in descending order. In order to avoid the sinking of blood cells, the choice of shear rate should not be too much, and the retention time should not be too long. (4) After each sample is measured, the sample cup should be cleaned and dried. Not suitable for the crowd There are no special taboos. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.