Plasma coagulation factor Ⅱ activity assay

Plasma coagulation factor II activity is measured by measuring blood coagulation factor II, prothrombin, and has diagnostic guidance for acute hepatitis and chronic hepatitis. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: After 8 pm on the day before the medical examination, you should fast, so as not to affect the detection of indicators such as blood glucose in the second sky. Normal value The normal value is 2 to 4 mg/mL. Clinical significance Abnormal result Coagulation factor II activity was normal or mildly decreased. In patients with moderate, severe and cirrhosis of chronic hepatitis, the level of coagulation factor II activity decreased significantly, indicating that its degree of reduction is closely related to the degree of hepatocyte damage. Some studies have suggested that abnormal protein prothrombin (protein-II induced by vitamin Kambence, PIVKA-II) can be used for the diagnosis of primary liver cancer. Some AFP-negative primary liver cancer patients are positive for PIVKA-II. Clinically, AFP and PIVKA-II should be combined. . People who need to be examined have people with symptoms of chronic hepatitis. Low results may be diseases: chronic hepatitis, cirrhosis, precautions Taboo before the test: Do not eat too greasy, high-protein foods the day before the test, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, you should fast. Requirements for examination: When taking blood, you should relax your mind to avoid the contraction of blood vessels caused by fear and increase the difficulty of blood collection. Inspection process Vascular blood collection was used for testing. Before venous blood collection, carefully check that the needle is securely installed and that there is air and moisture in the syringe. The needle used should be sharp, smooth, ventilated, and the syringe should not leak. Firstly, the skin was disinfected from the inside to the outside and clockwise from the selected venipuncture with a 30g/L iodine swab. After the iodine was volatilized, the iodized trace was wiped out in the same way with a 75% ethanol swab. Fix the lower end of the venipuncture site with the thumb of the left hand, hold the syringe syringe with the thumb and middle finger of the right hand, and fix the needle lower seat with the index finger, so that the bevel of the needle and the scale of the syringe are upward, and the needle is inclined along the vein to make the needle and the skin obliquely penetrate the skin at an angle of 30°. Then, through the vein wall, enter the venous cavity forward at an angle of 5°. After seeing the blood return, the needle will be probed into the spot to avoid the needle slipping out when the blood is collected; but it is not possible to use a deep puncture to avoid hematoma, and immediately remove the cuff. Needle plug can only be pumped out, can not be pushed in, so as to avoid injecting air into the vein to form a gas plug, causing serious consequences. Remove the syringe needle and slowly inject the blood into the anticoagulation tube along the tube wall to prevent hemolysis and foam. Not suitable for the crowd A patient with hemophilia and severe clotting factor deficiency. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.