Androstenedione

The biological activity of androstenedione is between the highly active androgen testosterone and the weak androgen dehydro androsterone. Androstenedione has the properties of a prohormone. 50% of the male androstenedione is from the ovary and 50% is from the adrenal gland. The daily yield of women exceeds 3000 μg, which is higher for men. Adult male androstenedione levels were slightly lower in women of the same age, and menopausal women decreased in the blood circulation due to decreased levels of adrenal and ovarian. Basic Information Specialist classification: growth and development check classification: endocrine examination Applicable gender: whether men and women apply fasting: not fasting Analysis results: Below normal: Found in adrenal insufficiency, ovarian dysfunction, sickle cell anemia, male development delay. Normal value: Serum A (male): 3.5-7.5 nmol/L Serum A (female): 4.5-10.8 nmol/L Above normal: Found in female hirsutism, hemorrhoids, congenital adrenal hyperplasia, adrenal cortical tumors, polycystic ovary syndrome, application of clomiphene or HCG. negative: Positive: Tips: Barbiturate sedatives, clomiphene citrate, gonadotropins and oral contraceptives can increase testosterone; androgen, dexamethasone, digoxin and alcohol make the results low. Normal value Male (6.3 ± 1.7) nmol / L (3.5 ~ 7.5 nmol / L). Female (7.1 ± 2.0) nmol / L (4.5 ~ 10.8nmol / L). Clinical significance The normal men's androstenedione is secreted 10 times as much as testosterone. Androstenedione can also be detected in female ovaries, and the level of androstenedione in females with masculinized diseases can be increased. Congenital adrenal hyperplasia can be increased, polycystic ovarian disease, androstenedione is normal or slightly elevated, hirsutism increased. Androstenedione reduces male developmental delay (1.6 to 3.0 nmol/L), dwarfism. Low results may be diseases: high adrenal insufficiency may result in diseases: precautions for male breast hypertrophy Barbiturate sedatives, clomiphene citrate, gonadotropins and oral contraceptives can increase testosterone; androgen, dexamethasone, digoxin and alcohol make the results lower. Inspection process The coated tubes were numbered, and then operated in sequence, the reaction solution was aspirated, and washed 3 times with water to measure the precipitate cpm value. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally not.