basophilic stippled red blood cells

Spotted red blood cells are a kind of naive red blood cells. In addition to hemoglobin, the cells also contain basophilic substances, which are dyed by basic dyes to form a large number of small blue particles called spotted red blood cells. Unlike reticulocytes, spotted red blood cells are stained with a dried blood film because the spot color is formed during cell drying. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Please follow the doctor's arrangements when checking. Normal value Microscopic counting The percentage is about 0.0001 (about 0.01%). Absolute value <300/106 red blood cells (<300/million red blood cells). Clinical significance Increased poisoning of heavy metals (lead, mercury, silver, strontium), increased toxicity of organic compounds (nitrobenzene, aniline), hemolytic anemia, pernicious anemia, leukemia, malignant tumors, pneumonia in children, etc. also increased. Precautions (1) The blood film should be pushed thinner so that the red blood cells do not overlap. (2) After the blood film is made. The drying speed should be slower, so that the formed dots are larger. Inspection process (1) A thin blood film is prepared by a usual method, dried and fixed with methanol. (2) Dye with alkaline methylene blue for about 40 s, wash with water, and dry. (3) Use a low power microscope to select the area where the red blood cells are evenly distributed, and then change the oil to the mirror. The red blood cells are light blue and the spotted particles are dark blue. (4) Counting method: basically the same as reticulocytes. The number of red blood cells in the 50 fields of view is counted, and the total number of red blood cells in the five fields is counted, and the percentage of the colored red blood cells can be calculated. For example, there are 15 red blood cells in 50 fields, and the total number of red blood cells in 5 fields is 1000. Not suitable for the crowd No taboos. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.