growth hormone

Human growth hormone is a protein secreted by pituitary cells. Under normal circumstances, growth hormone is pulsed secretion, its secretion is regulated by growth hormone releasing hormone (GHRH) produced by the hypothalamus, and is also affected by gender, age and circadian rhythm. The main physiological function of growth hormone is to promote the growth of all other tissues other than nerve tissue, promote the body's anabolism and protein synthesis, promote fat decomposition, antagonize insulin, inhibit glucose utilization and increase blood sugar. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: not fasting Tips: elevated serum growth hormone is also seen in strenuous activities, sleep, physical exercise, long-term fasting. Normal value The umbilical cord is 10 to 50 μg/L (10 to 50 ng/ml). Newborns 15 ~ 40μg / L (15 ~ 40ng / ml). Children <20 μg / L (<20ng / ml). Adult male <2μg / L (<2ng / ml). Female <10 μg / L (<10 ng / ml). Adult non-basal values ​​<10 μg / L (<10 ng / ml). Clinical significance (1) rise 1 pituitary tumor acromegaly, pituitary giant disease. 2 non-pituitary tumor diabetes, partial liver disease, renal insufficiency, pancreatic cancer. Inhibition tests can be used to identify an increase in GH caused by non-pituitary tumors. (2) lower 1 pituitary dwarfism and other causes of anterior pituitary dysfunction. 2 GH value caused by non-pituitary disease reduces liver cirrhosis, brain tumor near the pituitary. Excitatory tests can be used to identify reductions in pituitary and non-pituitary. Normal value of growth hormone-L-dopa stimulation test (fasting): peak >7 μg/L, or more than 5 μg/L before excitement (peak >7 ng/ml, or more than 5 ng/ml before excitement). Normal value of growth hormone-glucagon stimulation test (fasting): Increase to 7μg/L or more after excitement, or increase by more than 5μg/L before excitement (up to 7ng/ml or more before excitement, or 5ng/ml before excitement) The normal value of growth hormone-arginine stimulation test: fasting value <5μg / L (<5ng / ml), test 30 ~ 60min, rose to 7μg / L (7ng / ml) or more [peak range of 8 ~ 35μg / L ( 8 ~ 35ng / ml)]. Precautions (1) elevated serum growth hormone is also seen in strenuous activities, sleep, physical exercise, long-term fasting. Obese people can reduce serum growth hormone. (2) Intake of insulin, levodopa, niacin can increase growth hormone; intake of corticosteroids and glucose can reduce growth hormone. Inspection process Serum samples must be stored frozen at -30 °C until they are tested. Not suitable for the crowd no. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.