renal plasma flow

Renal plasma flow (RPF), which refers to the amount of plasma flowing through the kidneys per unit time. If a substance in the blood can be filtered by both the glomerulus and the renal tubules, the clearance rate is a combined result of glomerular filtration and tubular excretion. If the substance is completely removed after 1 week of renal circulation, the plasma clearance of the substance is equal to the plasma flow within 1 min of the kidney. Basic Information Specialist classification: urinary examination classification: urine / kidney function test Applicable gender: whether men and women apply fasting: fasting Tips: Please relax when checking. Normal value 600 ~ 800ml / min. Clinical significance Reduce cardiac output, renal arterial lesions, renal dysfunction. Low results may be diseases: renal vascular hypertension, elderly diabetic nephropathy, children with hypertension considerations About 20% of the plasma is filtered through the glomerulus, and the resulting filtrate is about 120-160 ml/min. The amount of plasma fluid filtered out through the glomerulus per unit time (minutes) is called the glomerular filtration rate. Inspection process (1) On the test day, the patient was placed on an empty stomach, and at 7 o'clock, 500 ml of water was given, and the catheter was indwelled. (2) Take 10 ml of urine at 7:30, and take 2 ml of venous blood (test blank). (3) Immediately, a sterile 200 g/LPAH solution was intravenously injected at 0.4 ml/kg body weight within 10 min, and then 500 ml of physiological saline solution was added to a solution of 10 g of a 200 g/LPAH solution for maintenance infusion. (4) At 8:30, the catheter is clamped. At 8:50, 4 ml of venous blood was taken, followed by emptying the bladder and measuring the amount of urine. The bladder was rinsed with 20 ml of physiological saline, and 20 ml of air was injected to drain the fluid in the bladder. The rinse solution was combined with urine, mixed, and 10 ml was taken to determine the PAH content. (5) At 9:10, the first blood sampling and urine retention specimens were repeated; at 9:20, the second blood sampling and urine retention specimens were repeated (same operation 4). (6) Determination of PAH concentration. Mix each time the reagent is added and place for 3 min. The color development was stable (10-15 min) and the blank tube was zeroed at 540 nm, and the absorbance values ​​of the tubes were read. (7) Determination of renal plasma flow. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.