prostate specific acid phosphatase

Prostate-specific acid phosphatase (PAP) is an acid phosphatase isoenzyme produced by lysosomes of prostate epithelial cells. It is a glycoprotein composed of two identical subunits with a molecular weight of 100 kD and an isoelectric point. 4.4 to 5.5, the half-life is 1.1 to 2.6 hours. The acid phosphatase in male serum is mainly derived from the prostate, while the activity of acid phosphatase in prostate tissue is 1000 times higher than that in other tissues. Basic Information Specialist classification: male examination inspection classification: biochemical examination Applicable gender: whether the male is fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value 0 to 2.1 μg/L. Clinical significance Abnormal result (1) The serum PAP level of patients with prostate cancer was significantly increased, and the level of PAP increased with the progress of prostate cancer. The metastasis was more obvious than that of non-metastatic patients. It is suggested that serum PAP detection has certain clinical significance for the staging and prognosis of prostate cancer. (2) elevated serum PAP levels can also be found in other malignant tumors such as osteosarcoma, multiple myeloma and other bone metastases. (3) In some non-neoplastic diseases such as benign prostatic hyperplasia, hyperparathyroidism, osteoporosis, etc., serum PAP levels may also increase, but the measured values ​​are lower. The people who need to be examined have people with frequent urination, urgency, dysuria, hematuria, and bone pain. High results may be diseases: precautions for prostate cancer Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Inspection process: The blood volume is about 5 mL. After blood collection, check with an antibody test. Not suitable for the crowd Have a coagulopathy such as hemophilia. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.