prothrombin consumption correction test

Under physiological conditions, blood coagulation requires a large amount of prothrombin, and there is little prothrombin remaining in the serum after coagulation, and the serum prothrombin time is prolonged. If the blood coagulation factors VIII, IX, XI, and XII are defective, the production of thromboplastin is poor, and the consumption of prothrombin is reduced. Therefore, more prothrombin remains in the serum, and the prothrombin time is shortened. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value Prolongation of serum prothrombin time to greater than 25 seconds is corrected. Clinical significance Abnormal result 1. Can be corrected by plasma containing factors VIII, IX, XI, suggesting the lack of factor VIII, found in hemophilia A, diffuse intravascular coagulation. 2. Can be corrected by plasma containing factors IX, XI, XII, suggesting the lack of factor IX, found in hemophilia B, liver disease, vitamin K deficiency. 3. Can be simultaneously corrected by the adsorption of plasma containing factors VIII, IX, XI and the fresh serum of factors IX, XI, XII, suggesting the lack of factors XI, XII, found in factor XI, XII deficiency, liver disease and so on. 4. If the adsorbed plasma containing factors VIII, IX, XI and the fresh serum of factors IX, XI, and XII cannot be corrected, it indicates that there is anticoagulant substance in the blood circulation, such as heparin. 5. Can be corrected by erythropoietin, suggesting erythropoietin deficiency, found in congenital or acquired platelet factor 3 deficiency, thrombocytopenia. Precautions Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. 4. It is forbidden to take anticoagulants, such as aspirin, before the test. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Inspection method: draw blood. Not suitable for the crowd Have a coagulopathy such as hemophilia. Adverse reactions and risks Infection: Do not touch the dirt after blood collection. Do not wash your hands immediately to avoid infection.