Viper Venom Time

Viper venom is a strong activator of factor X. It can bind to factors V, X and platelet factor 3 (PF3) to form exogenous prothrombinase to coagulate blood without the involvement of factor VII. When the test plasma lacks factors II, V, and X, blood coagulation will cause an obstacle, and when the plasma levels of the test factors II, V, and X are normal, blood coagulation can be accelerated. Basic Information Specialist classification: skin examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: When you take blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Normal value 13 ~ 14s, more than 3s than the normal control is abnormal. Clinical significance Abnormal results RVVT prolonged, seen in 1. Factor II, V, X and fibrinogen are reduced. 2. Thrombocytopenia or platelet function deficiency diseases such as thrombocytopenia; 3. Increased anticoagulant substances in the circulation, such as heparin. RVVT shortened, seen in 1. Thrombocytopenia. 2. Hyperlipidemia. 3. Prethrombotic state and thrombotic disease. Need to check patients with suspected conditions. Low results may be diseases: high results of essential thrombocytosis may be diseases: precautions for thrombocytopenia Contraindications before examination: When taking blood, you should relax your mind, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Requirements for inspection: (1) The venom dilution is unstable. If carbonic acid is added, it can be stored at 4 °C. If it is not added, it should be stored at -20 °C for about 20 days. (2) This test is used to identify factors VII and X. In the absence of Factor VII, the test was normal and plasma prothrombin time was prolonged; in the absence of Factor X, both the test and plasma prothrombin time were prolonged. This point has great practical significance. (3) Take 2ml of venous blood and test it with anticoagulation after citrate. Inspection process After blood was drawn, the frog venom phospholipid time and the frog venom recalcification time were determined using the frog venom reagent. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally not.