simple thromboplastin correction test

The simple thromboplastin production corrective test is mainly used to check the first stage of the endogenous coagulation system. Because of the shortcomings of Bigg's thromboplastin test (TGT), such as labor, blood consumption and time-consuming, Xu Fuyan et al first reported the simple thromboplastin test (STGT) and its corrective test in 1965. It is an endogenous coagulation pathway, especially a corrective test for the diagnosis of hemophilia. When the results of the simple thromboplastin test are greater than 15 seconds, normal human barium sulfate is used to adsorb plasma and normal human serum to correct the patient's recommended thromboplastin production. For example, using normal adsorbed plasma containing factors VII, VIII, XI, or normal serum containing factors IX, XI, XII, or normal adsorbed serum containing factors XI, XII and normal fresh plasma for corrective testing to determine what is lacking clotting factor. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Stop anticoagulant drugs and antiplatelet drugs before the test, so as not to affect the results of the corrective test. Normal value After adding various corrected plasma or serum, the extension time is corrected to within the normal range (ie, 10 to 15 seconds). Clinical significance Abnormal result 1. When adding normal human barium sulfate to absorb plasma, the patient's simple thromboplastin can be corrected, suggesting that factor VIII is lacking, which is found in hemophilia A. 2. When normal human serum is added to correct the patient's simple thromboplastin production, it indicates that factor IX is absent and is found in hemophilia B. 3. Weak normal human serum and normal human barium sulfate adsorption plasma can correct the patient's thromboplastin production, indicating that factor XI is lacking, found in hemophilia C. 4. If normal human barium sulfate adsorption serum and normal human serum cannot be corrected, it means that there is anticoagulant in the blood of the patient. People who need to be tested Hemophilia, liver disease, and vitamin K deficiency. Precautions Before the test: the application of anticoagulant drugs and antiplatelet drugs can affect the results of the corrective test. It is best to stop these drugs before the test. During the examination: should relax, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Not suitable for the crowd: no. Inspection process Blood test. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally not.