Thyroxine-binding globulin

Thyroxine-bindingglobulin (TBG) is an acidic glycoprotein composed of four subunits synthesized by the liver with a molecular weight of 60 kD. TBG is the main carrier protein of thyroid hormone in the blood circulation. It plays an important role in the storage, transportation, metabolism of thyroid hormone and the maintenance of the concentration of thyroid hormone and the dynamic stability of free thyroid hormone. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Below normal, it is easy to cause hyperthyroidism. Normal value: Male: 13.7-20.3μg/L Female: 13.7-21.5μg/L Above normal: Severe liver disease, increased TBG in the blood due to increased TBG synthesis and release. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before, and avoid heavy drinking. Normal value Male 17±3.3μg/L, female 17.6±3.9μg/L. Clinical significance Abnormal result (1) Serum TBG levels in patients with hyperthyroidism are significantly reduced. After the disease is relieved, TBG can gradually rise to normal levels. (2) When hypothyroidism, the degradation rate of TBG is slowed down, and the concentration of TBG in blood can be significantly increased, which can gradually decrease with the relief of the disease. (3) Congenital hyper-TBG and hereditary TBG deficiency may increase or decrease TBG. (4) Severe liver disease, increased TBG in the blood due to increased synthesis and release of TBG. Atherosclerosis, severe diabetes or malnutrition and other diseases, blood TBG decreased. (5) Estrogen, glucocorticoids and other drugs can affect the level of serum TBG, and TBG increases or decreases. People who need to be tested: sweating, eye protrusion, fatigue, skin disease, cirrhosis, etc. Low results may be diseases: Pregnancy with hyperthyroidism, pregnancy with hyperthyroidism Before the test: Do not eat too greasy, high-protein food the day before, avoid heavy drinking. The alcohol content in the blood will directly affect the test knot. After fasting for 12 hours before taking blood, take fresh blood for inspection. During the examination: should relax, avoid the contraction of blood vessels caused by fear, and increase the difficulty of blood collection. Not suitable for the crowd: no. Inspection process After the blood was drawn, it was detected by chemiluminescence. Not suitable for the crowd Generally no taboos are taken. Adverse reactions and risks Generally not.