Thyroglobulin

Thyroglobulin (Tg) is a macromolecular glycoprotein synthesized by thyroid follicular epithelial cells. It is the main component of the thyroid follicular glial. The synthetic thyroid hormone is stored in the follicular cavity as globulin. Under normal conditions, only a very small amount of Tg enters the blood circulation. Basic Information Specialist classification: Oncology examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein food the day before, avoid heavy drinking. Normal value 11.4 ~ 20.2mg / L. Clinical significance Abnormal result (1) Changes in serum Tg are more common in malignant tumors of the thyroid gland. For example, Tg may increase in different degrees in thyroid follicular carcinoma, papillary thyroid carcinoma and metaplastic carcinoma; and thyroid medullary carcinoma may have Tg. Normal or lower. The former is mainly due to the destruction of the thyroid gland and the secretion of a certain amount of Tg by the tumor tissue, and the Tg is increased in the blood; the latter tumor tissue is derived from thyroid C cells, not thyroid epithelial cells, so the serum Tg is not elevated. (2) Thyroid disease, thyroid tumor, subacute thyroiditis and chronic lymphocytic thyroiditis and other thyroid diseases can increase blood Tg levels. People who need to be tested Heart palpitations and appetite are obviously hyperactive, but weight loss, fatigue, weakness, cold, dry skin, less sweat, rough, yellow, cold and so on. High results may be diseases: nodular goiter, neuroendocrine tumor skin metastasis, thyroid-free cretinism in children, subclinical hypothyroidism, subclinical hyperthyroidism, simple goiter, hyperthyroidism in the elderly , selective IgA deficiency, radiation thyroiditis, thyroid cancer precautions Before inspection: Do not eat too greasy, high-protein food the day before, avoid heavy drinking. The alcohol content in the blood will directly affect the test results. Before the test, fasting for 12 hours, taking fresh blood for inspection. When checking: Should relax, avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Not suitable for the crowd: no. Inspection process After the blood was drawn, it was examined by chemiluminescence. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally not.