red blood cell lifespan

The life span of red blood cells is 100-130 days, with an average of about 125 days. In addition, the use of 51 chromium-labeled red blood cells in the circulating blood is reduced by 50%, that is, the T50 half-life is used as a clinical indicator. This method is simpler, and the normal person is 25 to 40 days, less than 20 days. In order to shorten, 17 days or less is significantly shortened, and the life span of red blood cells in patients with hemolytic anemia is significantly shortened. For example, sickle cell anemia is shortened to 5 to 15 days, and paroxysmal nocturnal hemoglobinuria (PNH) is shortened to about 10 days. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: not fasting Tips: Stop taking vitamin C one week before the test, because it can reduce the hexavalent 51Cr to trivalent and reduce the labeling rate. Normal value The radioactivity of the red blood cells is measured by radioactivity. The life span of normal human red blood cells is 100 to 130 days, with an average of about 125 days. The 51Cr-labeled red blood cell method has a half-life of 26.57±3.11 days and an average life span of 46-90 days. Clinical significance Abnormal results: reduce all types of hemolytic anemia. People who need to be examined: anemia, cell hemolysis, proteinuria. Low results may be diseases: congenital erythropoiesis abnormal anemia, globin-forming anemia, congenital aplastic anemia, pediatric congenital erythropoiesis anemia, hemoglobin M disease, hemoglobin E disease, hemoglobin D disease, hemoglobin C disease, globin-forming anemia retinopathy, oral polycythemia considerations Before the test: Stop taking vitamin C once a week, because it can reduce the mark rate by reducing the hexavalent 51Cr to trivalent. After the test: can help determine whether there is a related disease according to different red blood cell life. Inspection process Use radionuclides to label red blood cells in vivo or in vitro, and observe the rate of radioactivity disappearance in these labeled red blood cells, thereby obtaining the percentage of daily red blood cell death or the red blood cell renewal score. The time required for 100% update is red blood cell life. In addition, radionuclides can also be used to participate in erythropoiesis, and the time of disappearance of radioactivity in red blood cells can be measured to determine the life span of red blood cells. Not suitable for the crowd Blood was transfused during the first three weeks of the examination and during the examination. Adverse reactions and risks Infection: Do not touch the dirt after blood collection. Do not wash your hands immediately to avoid infection.