erythrocyte pyruvate kinase

Erythrocyte enzymes play an important role in regulating red blood cell metabolism. PK is a transferase in cell lysosomes. Enzyme deficiency leads to a decrease in energy supply, and shortened red blood cell life causes hemolytic anemia. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. Normal value The International Hematology Committee had a red blood cell PK15.0±1.99u/gHb, which was not significantly different between men and women (P>0.05). Clinical significance Abnormal results Pyruvate kinase (PK) deficiency is autosomal recessive, leading to non-spherical erythrocyte hemolytic anemia, it can also be secondary to some patients with myelodysplastic syndrome MDS, leukemia and aplastic anemia. People who need to be examined if there are jaundice, anemia, hepatosplenomegaly, high fever, pale, back pain, shortness of breath, fatigue, irritability and other symptoms. Precautions Before inspection: 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. After inspection: 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process The examination process: blood collection, blood sampling, general venous blood, blood drawn by a doctor or nurse, the amount of blood is determined according to the different content of the test and the number of items, the blood volume is generally 2-20 ml, Do not exceed 50 ml at most, and then the doctor will perform a protein color test. Not suitable for the crowd Have a coagulopathy such as hemophilia. Adverse reactions and risks Bleeding: After blood collection, use sterile cotton lump or other disinfecting hemostatic articles to tighten the needle to stop bleeding, especially for patients with coagulopathy should be given sufficient time to avoid bleeding.