Recalcification crossover test (CRT, PRT)

Calcium crossover test can be used for differential diagnosis of hemorrhage, preliminary screening of patients, calcium crossover test can distinguish the cause of prolonged calcium recalcification, identify the lack of coagulation factors or the presence of anticoagulant substances in circulating blood, the test is simple and practical Patients with coagulopathy, patients with hypercoagulability, and patients with cardiovascular disease. Basic Information Specialist classification: growth and development examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Check the day should be fasting. Normal value Test tube method, surface dish method 1.5 to 3 min. Clinical significance Abnormal results: The prolonged recalcification time (RT) can be corrected by 1/lO volume of normal human mixed plasma, indicating that the patient has defects in endogenous coagulation system coagulation factors (such as factor VIII, factor IX and factor XI); The prolonged recalcification time cannot be corrected by the equal amount of normal human mixed plasma, indicating that the patient's blood contains pathological anticoagulant substances. Need to check the crowd: Patients with coagulopathy, patients with hypercoagulability, and patients with cardiovascular disease. High results may be diseases: disseminated intravascular coagulation considerations Requirements for inspection: 1, blood should be smooth, there should be no blood coagulation and hemolysis. 2. Use sodium citrate as an anticoagulant. 3, can be used as an indicator of heparin monitoring. 4. This test is slightly more sensitive than CT and can detect patients with factor VIII: C<4%. Preparation before inspection: 1. The day of the test should be fasted. 2, not suitable for the crowd: there is no suitable for the crowd. Inspection process At 37 ° C, activate the coagulation factors XII and XI with activator (white clay, diatomaceous earth, attapulgite clay), add partial thromboplastin instead of platelets to provide phospholipids, and then add appropriate amount of calcium ions to meet endogenous anticoagulation All the conditions of blood. The time required to add calcium ions to plasma coagulation is called the activated partial thromboplastin time. It is a sensitive and commonly used screening test for endogenous coagulation systems. Not suitable for the crowd No taboos. Adverse reactions and risks Discomfort: There may be pain, swelling, tenderness, and visible subcutaneous ecchymosis at the puncture site.