aspirin tolerance test

The aspirin tolerance test is an extension of the bleeding time after taking a certain amount of aspirin. For the diagnosis of vascular pseudohemophilia. It is indicated that aspirin affects the formation of thromboxane A2 and interferes with the release of endogenous ADP by inhibiting platelet cyclooxygenase, and may have von Willebrand's disease. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: The bleeding time of normal people before and after taking the medicine is similar or prolonged by less than 2 minutes. Positive: The bleeding time after taking the drug was positive compared with the prolongation of more than 2 min before taking the drug. Tips: Before the examination, the diet is light and alcohol is prohibited. Check for an empty stomach in the morning. Guarantee a good night's sleep. Normal value The bleeding time 2 hours and 4 hours after taking the drug was negative compared with the pre-dose control for 2 minutes or less. Clinical significance Abnormal result The test results were positive, indicating that aspirin affects the formation of thromboxane A2 and interferes with the release of endogenous ADP by inhibiting platelet cyclooxygenase, possibly with von Willebrand's disease. People who need to be examined have spontaneous, minor injuries, and people who have a tendency to bleed for a long time after surgery. Positive results may be diseases: thrombocytopenic purpura considerations (1) If the bleeding time before taking the drug exceeds 6 minutes and is allergic to aspirin, this test should not be determined. (2) Aspirin has side effects of bleeding, and it is forbidden to perform this test for patients who are going to undergo surgery or within 1 week after surgery and with hemophilia. Inspection process (1) Within 5 days before the test, the patient was banned from any drugs containing aspirin and other drugs that affected the bleeding time. (2) Determine the bleeding time before taking the drug. (3) Oral aspirin 0.6g, serving 0.3g under 6 years old, and drinking 200ml at the same time. (4) The bleeding time is measured 2 hours after taking the drug. If the result is suspicious, the bleeding time can be repeated once after 4-6 hours. Not suitable for the crowd Forbidden people: those who are allergic to aspirin, those with hemophilia, those who have had a bleeding time of more than 6 minutes, are ready to undergo surgery or within 1 week after surgery. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.