aspirin tolerance test

Aspirin inhibits the release of endogenous adenosine monophosphate (ADP) from platelets, affecting platelet aggregation and prolonging bleeding time. In addition, the acetic acid chain of aspirin can inhibit cholinesterase, block the hydrolysis of choline acetate, cause microvascular dilation of the microcirculation, and prolong the bleeding time. This test is mainly used to diagnose certain bleeding disorders. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: The bleeding time of normal people before and after taking the medicine is similar or prolonged by less than 2 minutes. Positive: The bleeding time after taking the drug was positive compared with the prolongation of more than 2 min before taking the drug. Tips: Before the examination, the diet is light and alcohol is prohibited. Check for an empty stomach in the morning. Guarantee a good night's sleep. Normal value The bleeding time 2 hours and 4 hours after taking the drug was negative compared with the pre-dose control for 2 minutes or less. Clinical significance The bleeding time at 2 hours and 4 hours after taking the drug was positive for more than 2 minutes with the pre-dose control. Positive results were seen in patients with von Willebrand disease. Special Note: a) If the patient's original bleeding time is more than 6 minutes, it is not suitable for this test; b) The bleeding time is measured before taking the drug and 2 hours after taking the drug. If the result is not accurate, it can be retested after 4 hours. Positive results may be diseases: precautions for acquired platelet dysfunction (1) If the bleeding time before taking the drug exceeds 6 minutes and is allergic to aspirin, this test should not be determined. (2) Aspirin has side effects of bleeding, and it is forbidden to perform this test for patients who are going to undergo surgery or within 1 week after surgery and with hemophilia. Inspection process (1) Within 5 days before the test, the patient was banned from any drugs containing aspirin and other drugs that affected the bleeding time. (2) Determine the bleeding time before taking the medicine. (3) Oral aspirin 0.6g, serving 0.3g under 6 years old, and drinking 200ml at the same time. (4) The bleeding time is measured 2 hours after taking the drug. If the result is suspicious, the bleeding time can be repeated once after 4-6 hours. Not suitable for the crowd Forbidden people: those who are allergic to aspirin, those with hemophilia, those who have had a bleeding time of more than 6 minutes, are ready to undergo surgery or within 1 week after surgery. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.