Mean Platelet Volume (MPV)

The detection of platelets is helpful for the diagnosis of hemorrhagic diseases. It has important significance for the study of the pathogenesis of prethrombotic state and thrombotic diseases, the therapeutic effect of antithrombotic drugs and the screening of antiplatelet drugs. Basic Information Specialist classification: cardiovascular examination classification: blood examination Applicable gender: whether men and women apply fasting: fasting Tips: Please relax when you draw blood. Normal value (11.3 ± 1.7) fl (automatic blood cell analyzer). Clinical significance (1) The increase in mean platelet volume is seen in paroxysmal thrombocytopenic purpura, giant platelet syndrome, chronic myeloid leukemia, and thrombotic disease. (2) The average platelet volume reduction is seen in aplastic anemia, hypersplenism, and acute leukemia chemotherapy. (3) The change of the average platelet volume helps to identify the cause of thrombocytopenia. In general, the increase of peripheral platelet damage leads to an increase in MPV in thrombocytopenia, and the MPV of thrombocytopenia is reduced by bone marrow lesions. Infected patients, local inflammation When the MPV is normal or increased, half of the MPV is reduced in the case of sepsis. If the MPV continues to decrease with the number of platelets, it is a sign of bone marrow failure. The smaller the MPV, the more severe the bone marrow suppression. Low results may be diseases: children with adult chronic myeloid leukemia, hemorrhagic disease results may be high disease: hypersplenism, aplastic anemia, thrombocytopenic purpura, pediatric giant platelet syndrome precautions Judging bone marrow hematopoietic function: When bone marrow hematopoietic failure occurs, platelet mean volume and platelet count continue to decrease at the same time. The more severe the inhibition of hematopoietic function, the smaller the average platelet count. When the hematopoietic function is restored, the average platelet volume is first increased, and then the platelet count is increased. Inspection process Blood test. Not suitable for the crowd 1. Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the examination and prohibit patients who have recently taken the drug history. 2, special diseases: patients with hematopoietic function to reduce disease, such as leukemia, various anemia, myelodysplastic syndrome, etc., unless the examination is essential, try to draw less blood. Adverse reactions and risks 1, subcutaneous hemorrhage: due to pressing time less than 5 minutes or blood draw technology is not enough, etc. can cause subcutaneous bleeding. 2, discomfort: the puncture site may appear pain, swelling, tenderness, subcutaneous ecchymosis visible to the naked eye. 3, dizzy or fainting: in the blood draw, due to emotional overstress, fear, reflex caused by vagus nerve excitement, blood pressure decreased, etc. caused by insufficient blood supply to the brain caused by fainting or dizziness. 4. Risk of infection: If you use an unclean needle, you may be at risk of infection.