hepatitis B core antibody immunoglobulin G

HBcAb-IgG appears late and is not a protective antibody. The recovery period of acute infection and chronic persistent infection are mainly anti-HBc-IgG, which can last for several years. The detection of HBcAb-IgG has epidemiological significance. It has been proposed to simultaneously detect anti-HBc-IgM and anti-HBc-IgG, and compare the titers of both, such as IgM predominating for the recent infection, while IgG predominating for the previous infection. Basic Information Specialist classification: Infectious disease examination and classification: blood examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Normal value: no Above normal: negative: normal. Positive: Prompt immunity, no infection, only history of hepatitis B infection. Tips: According to the nutritional status of the whole body, milk, eggs, fruits, soy milk, etc. are given in the meal. Normal value negative. Clinical significance 1. Anti-HBc IgG alone shows immunity, no infection, only history of hepatitis B infection. 2. Both anti-HBcIgM and anti-HBcIgG positive hepatitis B tend to be chronic. Positive results may be diseases: hepatitis B, hepatitis B virus precautions It has been proposed to simultaneously detect anti-HBc-IgM and anti-HBc-IgG, and compare the titers of both, such as IgM predominating for the recent infection, while IgG predominating for the previous infection. Inspection process 1, according to the material: blood. 2, Hepatitis B core antibody immunoglobulin G determination principle: the same as anti-HAVIgM, using the sandwich method ELISA. 3, reagents: domestic commercial kits, containing anti-μ chain coated reaction plate (strip), hepatitis B virus core antigen HBcAg application solution, anti-HBcHRP application solution and anti-HBc-IgG negative, positive control serum , sample diluent, washing solution, substrate solution and stop solution and other reagents. 4. Operation method: Follow the instruction manual of the kit. The general kits are divided into two categories, namely a three-step method and a two-step method, and the specific operation is the same as the anti-HAV-IgM detection method. Not suitable for the crowd Generally no taboos. Adverse reactions and risks Generally no complications and harm.

Was this article helpful?

The material in this site is intended to be of general informational use and is not intended to constitute medical advice, probable diagnosis, or recommended treatments.