Basal gastric secretion/peak gastric secretion

Clinically, there are various methods for examining gastric acid secretion, such as gastric secretion test without giving any stimulant. The stimulating agent is used to directly or indirectly stimulate the secretory cells of the gastric mucosa to observe its secretory function, such as the pentagastrin gastrin test. In addition, through the stimulation of the vagus nerve, the observation of gastric secretion function, such as insulin-stimulated gastric secretion test, is selected according to clinical needs. Basic Information Specialist classification: Digestive examination classification: body fluid examination Applicable gender: whether men and women apply fasting: fasting Tips: Some patients with diseases are not suitable for this examination, such as esophageal stricture, esophageal varices, aortic aneurysm, severe hypertension, cardiovascular disease. Therefore, patients should tell their doctors their medical history in detail before deciding to do this test. Normal value <0.2 (<20%). Clinical significance Abnormal results: (1) elevation: duodenal ulcer Zollinger-Ellison syndrome (Zhuo-Ai syndrome), portal vein anastomosis, small bowel resection, carcinoid syndrome, severe central nervous system disease, pyloric obstruction, a small number of pancreas disease. (2) reduction: atrophic gastritis, gastric cancer, pernicious anemia, hyperthyroidism, long-term alcoholism, subacute combined degeneration of the spinal cord, stomach gangrene, oral infection and suppuration. People who need to be examined: those who have been drinking for a long time, those who have a good appetite but are getting thinner. Low results may be diseases: duodenal ulcer, atrophic gastritis, carcinoid syndrome, high results may be diseases: gastric cancer precautions Before inspection: 1 Some patients with diseases are not suitable for this examination, such as esophageal stricture, esophageal varices, aortic aneurysm, severe hypertension, cardiovascular disease. Therefore, patients should tell their doctors their medical history in detail before deciding to do this test. 2 2 days before this test, stop using drugs that affect the secretion of gastric juice, such as ranitidine, sucralfate and so on. 3 Because different diets have different effects on gastric juice secretion, it is forbidden to eat high-protein, high-fat foods 24 hours before the test, and do not drink alcohol: water is forbidden for 12 hours before the test. When checking: 1 Because mood swings can affect the secretion of gastric acid, so avoid mental stimulation before doing this test. 2 patients should not be nervous, should relax themselves and cooperate with the doctor. Inspection process (1) On the day before the analysis of gastric juice, various drugs that affect the secretion of gastric juice, such as atropine and probensin, were stopped. Fasted and banned after dinner (12 hours). (2) Checking the stomach in the morning on the morning, inserting the stomach tube from the nostrils, when the stomach tube is inserted into the pharyngeal gorge, there is often a feeling. At this time, the patient should take the active spring pharyngeal movement, and the operator will insert the stomach tube into the esophagus. If you have a sense of care through the pharyngeal gorge, deep breathing can be alleviated. When the stomach tube enters the esophagus and enters a length of about 56 cm, the gastric juice can be withdrawn, indicating that it has reached the stomach cavity. If the nasal cavity has a disease that cannot be inserted, it can also be inserted through the mouth. (3) Drain the fasting gastric juice. Then, the gastric juice was continuously extracted for 1 hour, the gastric juice was kept in the container, and the gastric acid was measured and measured. The gastric juice is usually taken once every 15 minutes for 4 times. The sum of gastric acid is called the amount of basal gastric acid secretion, expressed as BAO. The normal value is less than 5mmo1/hour. (4) Use a stimulant such as subcutaneous injection of histamine or subcutaneous injection of five gastrin. The gastric juice was then continuously aspirated, and the gastric juice was collected once every 15 minutes for 4 times. After the injection of the gastric acid stimulating agent, the total amount of gastric acid secretion collected four times in one hour is called the maximum gastric acid excretion. According to MAO, normal males were 18.02±8.84 mmo1/hour, and females were 13.43±7.98 mmo1/hour. The highest gastric acid output in two consecutive 15 minutes in 4 specimens was multiplied by 2, which is called the peak acid output, expressed as PAO. According to the application of the stimulant can be divided into 1 histamine test: subcutaneous injection of histamine phosphate 40 μg / kg body weight. 2 five gastrin test: the injection dose is 6 micrograms / kg body weight. Previously, a trial test was used, such as eating half a taro or two slices of bread and 400 ml of warm boiled water. Therefore, the method is not accurate and is not used now. (5) Inspection: The gastric juices taken at different times are examined, including general traits (color, taste, etc.), gastric acid determination, occult blood test, bacterial detection, and various cell analysis such as tumor cells. Not suitable for the crowd Some patients with diseases are not suitable for this examination, such as esophageal stricture, esophageal varices, aortic aneurysm, severe hypertension, cardiovascular disease. Adverse reactions and risks May cause an infection.