peak gastric acid secretion

When the maximum amount of gastric acid secretion was measured, the sum of the two measured values ​​of the highest gastric acid content in the four samples was multiplied by 2, which is the peak gastric acid secretion amount. It is directly related to the size of the cell wall of the gastric mucosa. Gastric acid in the gastric juice (0.2% to 0.4% hydrochloric acid) kills bacteria in the food, ensures the safety of the stomach and intestines, and increases the activity of pepsin to help digestion. Gastric juice plays an important role in digesting food. Normal gastric juice is acidic. It is 20~100ml on fasting. More than 100ml indicates increased gastric acid secretion. There is a certain amount of gastric secretion, such as excessive secretion, it will appear acid, nausea, vomiting acid and so on. Basic Information Specialist classification: Digestive examination classification: body fluid examination Applicable gender: whether men and women apply fasting: fasting Tips: prohibit eating, ban, and smoking for more than 8 hours before surgery, usually in the morning. Normal value The normal value of gastric acid secretion was 12.23~28.97mmol/h. Clinical significance Abnormal results: Reduced in atrophic gastritis, gastric cancer, gastric dilatation, pernicious anemia, oral purulent infection, hyperthyroidism and so on. Elevation is seen in duodenal ulcers and the like. A significant increase (>15 mmol/h) was seen in gastrinoma. Need to check the crowd for various reasons, resulting in irregular eating, cold and hot, hungry for a full meal; people who drink cold drinks, drink herbal tea; personality reasons, often sulking, leading to mentally ill people; need Those who take stimulating drugs for a long time; other people with gastric diseases are susceptible. Low results may be diseases: high gastric cancer results may be diseases: chronic gastritis, gastric ulcer, stomach, duodenal ulcer bleeding considerations Pre-examination requirements: pre-operative diet, drug ban, smoking ban for more than 8 hours, usually in the morning. Requirements for examination: Change position (up, side, prone and sitting position) according to the doctor's instructions. Inspection process Possible examination method: gastric tube collection method. method: 1. Insert the disinfected (cooked) stomach tube into the stomach through the nose or mouth, and reach the gastric large curved mucus pool at a depth of about 50-55 cm. 2. Use a 50ml syringe to connect to the outer end of the stomach tube to aspirate the gastric juice (or continue to attract with a negative pressure pump), fill it into the container after pumping, and then take the tube to continue pumping. 3. The patient changes position (up, side, prone and sitting position), and the liquid in the stomach is aspirated as much as possible. Then extubate. 4. Record the amount of gastric juice extracted, label it on the container for inspection, and check the thick mucus in the gastric juice with gauze, and then analyze the gastric juice according to the required items. 5. For the analysis of gastric juice of pentapeptide gastrin or high-dose histamine, it is necessary to take 1h of gastric juice before injection (the gastric juice initially taken out after intubation is discarded), and continue to take 1h after injection, every 15 minutes of gastric juice One bottle, the above 5 bottles of gastric juice were taken for inspection. Not suitable for the crowd Any esophageal varices, esophageal stenosis, esophageal tumor, aortic aneurysm, severe hypertension, cardiovascular disease, heart failure, late pregnancy, physical weakness and other serious diseases should not be inserted into the stomach tube. Adverse reactions and risks If coughing, difficulty breathing, cyanosis, etc. occur during intubation, it is suggested to enter the trachea. It should be pulled out immediately, and then rested after a short break.