Serum α-L-fucosidase (α-FU)

Serum α-L-fucosidase is a lysosomal acid hydrolase that catalyzes a bioactive macromolecular hydrolase containing fucosyl glycoproteins, glycolipids, etc., which is widely distributed in human tissue cells, blood and body fluids. in. Participation in the metabolism of glycoproteins, glycolipids and oligosaccharides in the body, due to the significant increase in serum α-L-fucosidase in patients with liver cancer, it is currently considered to be a new marker of liver cancer in primary liver cancer. Basic Information Specialist classification: Digestive examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. Normal value Enzyme rate method (37 ° C): (6.80 ± 1.49) U / L. Clinical significance Abnormal result 1. Reduction: seen in fucosidic storage disease (hereditary fucosidase deficiency). 2, elevated: seen in hepatocellular carcinoma, primary liver cancer, metastatic liver cancer, cirrhosis, acute hepatitis and so on. Low results may be diseases: high results of fucoside storage disease may be diseases: liver cirrhosis, metastatic liver cancer, primary liver cancer considerations First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process Immediately after venous blood collection, the test method was determined by the enzyme speed method. Not suitable for the crowd Those without examination indications should not be tested. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.