Cancer Antigen 242 (CA242)

CA242 is commonly used in the RIA method and is a specific tumor antigen for pancreatic cancer and gallbladder cancer. The carbohydrate antigen CA242 (CA242) is a monoclonal antibody raised from the human colorectal cancer cell line COLO205, and is also a sialylated glycosphingolipid antigen, which is co-expressed with CA50. Its biochemical nature is a sialylated carbohydrate structure, which belongs to mucin. It is present in normal pancreas and colonic mucosa, but its expression is extremely low. Basic Information Specialist classification: Oncology examination classification: immune examination Applicable gender: whether men and women apply fasting: fasting Tips: Before eating, the diet is light, alcohol is forbidden, and good sleep is guaranteed. Check for an empty stomach in the morning. Normal value RIA method <12U/ml. Clinical significance Elevation is seen in pancreatic cancer, gallbladder cancer (significantly elevated), colorectal cancer, and colorectal cancer liver metastasis. High results may be diseases: gallbladder cancer, gallbladder cancer in the elderly, pancreatic cancer, pancreatic cancer in the elderly, colorectal cancer First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the medical examination, you should start fasting for 12 hours to avoid affecting the test results. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. 3. Please inform the doctor about the recent medication and special physiological changes before the test. Inspection process Blood samples are taken for examination immediately after vening puncture, and tumor immunoassay is performed. Not suitable for the crowd Those without examination for appropriate symptoms should not be tested. Adverse reactions and risks 1. Infection: Pay attention to aseptic operation when collecting blood, avoid contamination of water and other parts at the blood collection site to avoid local infection. 2, bleeding: after the blood is given a full compression time, especially coagulopathy, bleeding tendency, to avoid local subcutaneous oozing, bruising and swelling.