Serum Manganese (Mn)

The human body contains 12 to 18 mg of manganese. Manganese is mainly absorbed in the intestines, and the absorption rate is also low due to the low solubility of manganese in food. Because manganese participates in the composition and activation of various enzymes, it is related to protein synthesis and improves lipid metabolism in atherosclerosis. Manganese can also promote the absorption and utilization of iron, participate in the synthesis of mucopolysaccharide (mucopolysaccharide is the main component of cartilage and bone tissue), and can resist oxidation and eliminate free radicals, and play a role in preventing cancer. Basic Information Specialist classification: Oncology examination classification: biochemical examination Applicable gender: whether men and women apply fasting: fasting Analysis results: Below normal: Reduced in various anemia, chronic lymphocytic leukemia, lymphogranuloma and so on. Normal value: Serum manganese (Mn): 73-255μmol/L Above normal: Increased in chronic manganese poisoning, myeloma and so on. negative: Positive: Tips: Do not eat too greasy, high-protein foods the day before the blood draw, avoid heavy drinking. The alcohol content in the blood directly affects the test results. After 8 pm on the day before the medical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. Normal value 73 to 255 μmol/L (0.4 to 1.4 μg/dl). Clinical significance 1. Reduced in various anemia, chronic lymphocytic leukemia, lymphogranuloma, etc. 2, increased in chronic manganese poisoning, myeloma and so on. Low results may be diseases: congenital nystagmus, anemia, chronic lymphocytic leukemia results may be high disease: manganese poisoning precautions First, the precautions before blood draw 1, do not eat too greasy, high-protein food the day before the blood, to avoid heavy drinking. The alcohol content in the blood directly affects the test results. 2. After 8 pm on the day before the physical examination, fasting should be done to avoid affecting the detection of indicators such as blood glucose in the second sky. 3, should relax when taking blood, to avoid the contraction of blood vessels caused by fear, increase the difficulty of blood collection. Second, should pay attention after blood draw 1. After blood is drawn, local compression is required at the pinhole for 3-5 minutes to stop bleeding. Note: Do not rub, so as not to cause subcutaneous hematoma. 2, the pressing time should be sufficient. There is a difference in clotting time for each person, and some people need a little longer to clotting. Therefore, when the surface of the skin appears to be bleeding, the compression is stopped immediately, and the blood may be infiltrated into the skin due to incomplete hemostasis. Therefore, the compression time is longer to completely stop bleeding. If there is a tendency to bleed, the compression time should be extended. 3, after the blood draw symptoms of fainting such as: dizziness, vertigo, fatigue, etc. should immediately lie down, drink a small amount of syrup, and then undergo a physical examination after the symptoms are relieved. 4. If there is localized congestion, use a warm towel after 24 hours to promote absorption. Inspection process 1, blood collection: take the right amount of blood, immediately sent for inspection. Whether using trace elements for serum, plasma or whole blood, the syringes and tubes must be thoroughly washed to reduce exogenous contamination. When the blood is collected, the skin is disinfected with alcohol (without iodine) 2 times, and 2 ml of blood is drawn. Serum was separated in time and placed separately to avoid hemolysis. 2. Detection method: (1) Atomic absorption spectrometry. (2) Emission spectrum analysis method. (3) Neutron activation analysis method. (4) X-ray fluorescence analysis. Not suitable for the crowd Patients who have taken contraceptives, thyroid hormones, steroid hormones, etc., may affect the results of the test, and patients with a history of drug administration in the near future are prohibited. Adverse reactions and risks Subcutaneous hemorrhage: subcutaneous hemorrhage due to less than 5 minutes of compression time or blood draw technique.